Evidence map›Paper›PMID 29777287›Full record

ArticlePsychopharmacology2018

Decreased plasma levels of gasotransmitter hydrogen sulfide in patients with schizophrenia: correlation with psychopathology and cognition.

Jian-Wen Xiong, Bo Wei, Yan-Kun Li, Jin-Qiong Zhan, Shu-Zhen Jiang, Hai-Bo Chen, Kun Yan, Bin Yu, Yuan-Jian Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Psychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Hydrogen sulfide/polysulfides signaling and neuronal diseases.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  4. Article
  5. Article
  6. Hydrogen Sulfide (HBiomolecules · 2024
    Review
  7. Article
  8. Review
  9. Hydrogen Sulfide (HBiomolecules · 2021
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jian-Wen XiongDepartment of Psychiatry, Jiangxi Mental Hospital/Affiliated Mental Hospital of Nanchang University, Number 43, Shangfang Road, Nanchang, 330029, People's Republic of China.
Bo WeiDepartment of Psychiatry, Jiangxi Mental Hospital/Affiliated Mental Hospital of Nanchang University, Number 43, Shangfang Road, Nanchang, 330029, People's Republic of China.
Yan-Kun LiDepartment of Pharmacology, School of Pharmacy, Hubei University of Science and Technology, Xianning, 437100, People's Republic of China.
Jin-Qiong ZhanMedical Experimental Center, Jiangxi Mental Hospital/Affiliated Mental Hospital of Nanchang University, Nanchang, 330029, People's Republic of China.
Shu-Zhen JiangDepartment of Pharmacy, Jiangxi Mental Hospital/Affiliated Mental Hospital of Nanchang University, Nanchang, 330029, People's Republic of China.
Hai-Bo ChenDepartment of Psychiatry, Jiangxi Mental Hospital/Affiliated Mental Hospital of Nanchang University, Number 43, Shangfang Road, Nanchang, 330029, People's Republic of China.
Kun YanMedical Experimental Center, Jiangxi Mental Hospital/Affiliated Mental Hospital of Nanchang University, Nanchang, 330029, People's Republic of China.
Bin YuDepartment of Psychiatry, Jiangxi Mental Hospital/Affiliated Mental Hospital of Nanchang University, Number 43, Shangfang Road, Nanchang, 330029, People's Republic of China. jxmh_yb@163.com.
Yuan-Jian YangDepartment of Psychiatry, Jiangxi Mental Hospital/Affiliated Mental Hospital of Nanchang University, Number 43, Shangfang Road, Nanchang, 330029, People's Republic of China. yuanjimyang@yeah.net.ORCID http://orcid.org/0000-0002-0175-5646
Nanchang University · CNHubei University of Science and Technology · CN

Funding

National Natural Science Foundation of China 81560232National Natural Science Foundation of China 81600939National Natural Science Foundation of China 81760254Natural Science Foundation of Hubei Province of China 2014CFB186Natural Science Foundation of Jiangxi Province of China 20151BBG70110Natural Science Foundation of Jiangxi Province of China 20161BAB205193
6 · The paper itself

Abstract

objectiveAberrant N-methyl-D-aspartate receptor (NMDAR) function has been implicated in the pathophysiology of schizophrenia. Hydrogen sulfide (H MATERIALS AND

methodsForty-one patients with schizophrenia and 40 healthy control subjects were recruited in present study. Schizophrenic symptomatology was assessed using the Positive and Negative Syndrome Scale (PANSS). Cognitive function was evaluated with a neuropsychological battery including seven neurocognitive tests. Plasma H

resultsPatients with schizophrenia performed worse in all of the cognitive tests than the healthy controls except for the visual memory. Plasma H

conclusionThe significant relations observed in the current study between H

Indexed as

Schizophrenic PsychologyAdultBiomarkersCognitionCognitive DysfunctionExecutive FunctionFemaleGasotransmittersHumansHydrogen SulfideMaleMemory, Short-TermMiddle AgedNeuropsychological TestsPsychopathologySchizophreniaBiomarkersGasotransmittersHydrogen SulfideCognitionHydrogen sulfidePsychopathologySchizophrenia

Identifiers

PMID29777287
OpenAlexW2804520547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.