ArticleNature immunology2018
Tuberculous meningitis: a roadmap for advancing basic and translational research.
Abstract readConference Proceedings
In one paragraph
Article in Nature immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- High dose of rifampicin in the treatment of tuberculous meningitis: a systematic review and meta-analysis of randomized controlled trials.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Pooled it
- A clinical practice guideline for tuberculous meningitis.The Lancet. Infectious diseases · 2026Guideline
- Prevalence, incidence, and case fatality of tuberculous meningitis in adults living with HIV: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Efficacy and safety of intrathecal dexamethasone combined with isoniazid in the treatment of tuberculous meningitis: a meta-analysis.BMC neurology · 2024Pooled it
- Cerebrospinal Fluid Transcriptional Immune Pathways Linked to Survival in HIV-Associated Tuberculous Meningitis.The Journal of infectious diseases · 2026Article
- Management ofOpen forum infectious diseases · 2026Article
- Metabolic insights into the pathophysiology of tuberculous meningitis in FFPE postmortem human brain tissue.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Addition of Clofazimine Enhances the Activity of Standard Treatment Regimen in a Mouse Model of Tuberculous Meningitis.The Journal of infectious diseases · 2026Article
- Beyond Rifampin: Evaluating Rifapentine and Rifabutin as Alternative Treatments for Tuberculous Meningitis.The Journal of infectious diseases · 2026Article
- Host-directed treatments for tuberculous meningitis utilizing a multi-platform approach across mouse and human models.Nature communications · 2026Article
- Host-directed treatments for tuberculous meningitis: A multi-platform approach across mouse and human models.Research square · 2026Article
- Clinical analysis of 19 patients with tuberculosis complicated by hemophagocytic lymphohistiocytosis.Frontiers in immunology · 2026Article
- Host-directed nanotherapy for the treatment and imaging of tuberculous meningitis.Theranostics · 2026Article
- Mycobacteria trehalose dimycolate interactions with host Mincle remodel blood-brain barrier junctions for brain invasion.Cell reports · 2025Article
- Predictors of Tuberculous Meningitis Mortality Among Persons with HIV in Mozambique.Tropical medicine and infectious disease · 2025Article
- Advances in management and treatment of tubercular meningitis - a narrative review.Annals of medicine and surgery (2012) · 2025Review
- Strategies for shortening tuberculosis therapy.Nature medicine · 2025Review
- Proapoptotic Bcl-2 inhibitor as potential host directed therapy for pulmonary tuberculosis.Nature communications · 2025Article
- Challenges of Multidrug-Resistant Tuberculosis Meningitis: Current Treatments and the Role of Glutathione as an Adjunct Therapy.Vaccines · 2024Review
- Spatially heterogeneous lipid dysregulation in tuberculous meningitis.Neurobiology of disease · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Sanjay K JainCenter for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA. sjain5@jhmi.edu.
David M TobinDepartments of Molecular Genetics and Microbiology and of Immunology, Duke University School of Medicine, Durham, NC, USA.ORCID http://orcid.org/0000-0003-3465-5518
Elizabeth W TuckerCenter for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Vishwanath VenketaramanDepartment of Basic Medical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Alvaro A OrdonezCenter for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-8571-0655
Lakshmi JayashankarColumbus Technologies, Inc., Contractor to the National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Bethesda, MD, USA.
Omar K SiddiqiGlobal Neurology Program, Division of Neuro-Immunology, Center for Virology and Vaccine Research, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Dima A HammoudCenter for Infectious Disease Imaging, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
Nemani V PrasadaraoSabin Research Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Matyas SandorDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Richard HafnerDivision of AIDS, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
Zsuzsanna FabryDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA. zfabry@wisc.edu.
NIH Tuberculous Meningitis Writing Group
Funding
Macrophage Reprogramming During Granuloma Formation in the ZebrafishR01AI130236 · NIAID · DUKE UNIVERSITY · PI David M. Tobin · 2017 to 2026
$4.5MGenetic dissection of angiogenesis in the tuberculous granulomaR01AI125517 · NIAID · DUKE UNIVERSITY · PI David M. Tobin · 2017 to 2026
$4.4MNovel Imaging Tracers for Rapid and Noninvasive Assessment of Bacterial InfectionR01EB020539 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2014 to 2018
$3.6MThe Genetic Basis of Bone Disease in Mycobacterial InfectionR01AI127715 · NIAID · DUKE UNIVERSITY · PI Clare Margaret Smith, David M. Tobin · 2017 to 2026
$3.3MMolecular Imaging for Pulmonary Infections and InflammationR01HL131829 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2016 to 2018
$2.2MCNS TuberculosisR01NS076946 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI FABRY, ZSUZSANNA · 2012 to 2016
$1.7MInnate immunity of granulomatous inflammation: the role of VEGFR01HL128778 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI SANDOR, MATYAS · 2016 to 2019
$1.5MNovel CSF Diagnostics and Genotype Markers of Tuberculous Meningitis in ZambiaK23NS084054 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SIDDIQI, OMAR KHALIK · 2014 to 2018
$910kCore Research Services for Molecular Imaging and Imaging SciencesZICCL040013 · CLC · CLINICAL CENTER · PI FRANK, JOSEPH · 2009 to 2025
$0kNHLBI NIH HHS R01 HL128778NHLBI NIH HHS R01 HL131829NIAID NIH HHS R01 AI125517NIAID NIH HHS R01 AI127715NIAID NIH HHS R01 AI130236NIBIB NIH HHS R01 EB020539NINDS NIH HHS K23 NS084054NINDS NIH HHS R01 NS076946
Abstract
PubMed holds no abstract for this paper.
Indexed as
Tuberculosis, MeningealAnimalsHumans
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.