ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2018
Influence of alcoholism and cholesterol on TSPO binding in brain: PET [
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Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 72 citations in OpenAlex.
- Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial.Addiction biology · 2022Trial
- Targeting neuroinflammation with minocycline in heavy drinkers.Psychopharmacology · 2019Trial
- Cytokine Networks in Alcohol Use Disorder: A Narrative Review Highlighting Research Gaps and Future Priorities.Medical sciences (Basel, Switzerland) · 2026Review
- MAO-B status in alcohol use disorder: a [Molecular psychiatry · 2026Article
- Early abstinence in severe alcohol use disorder: MCP-1 decline, choroid plexus shrinkage, and region-specific grey-matter volume changes.Translational psychiatry · 2026Article
- Greater Neuroimmune System Deficit in Women Than Men With Alcohol Use Disorder.Biological psychiatry · 2026Article
- TSPO circadian pattern: a test-retest study of [European journal of nuclear medicine and molecular imaging · 2025Article
- Circulating Immune and Endocrine Markers in Currently Drinking and Abstinent Individuals With Alcohol Use Disorder and Controls.Addiction biology · 2025Article
- Effects of Cigarette Smoking and 3-Day Smoking Abstinence on Translocator Protein 18 kDa Availability: A [Addiction biology · 2025Observational
- Molecular Imaging Studies of Alcohol Use Disorder.Current topics in behavioral neurosciences · 2025Review
- TSPO Radioligands for Neuroinflammation: An Overview.Molecules (Basel, Switzerland) · 2024Review
- Imaging neuroinflammation in individuals with substance use disorders.The Journal of clinical investigation · 2024Review
- Two-Month Voluntary Ethanol Consumption Promotes Mild Neuroinflammation in the Cerebellum but Not in the Prefrontal Cortex, Hippocampus, or Striatum of Mice.International journal of molecular sciences · 2024Article
- Transcriptional Dysregulation of Cholesterol Synthesis Underlies Hyposensitivity to GABA in the Ventral Tegmental Area During Acute Alcohol Withdrawal.Biological psychiatry · 2024Article
- Smoking, tobacco dependence, and neurometabolites in the dorsal anterior cingulate cortex.Molecular psychiatry · 2023Article
- Neuroimmune Mechanisms of Opioid Use Disorder and Recovery: Translatability to Human Studies, and Future Research Directions.Neuroscience · 2023Review
- Imaging the brain's immune response to alcohol with [Molecular psychiatry · 2023Article
- The vicious cycle between (neuro)inflammation and alcohol use disorder: An opportunity to develop new medications?Alcohol, clinical & experimental research · 2023Article
- Positron Emission Tomography of Neuroimmune Responses in Humans: Insights and Intricacies.Seminars in nuclear medicine · 2023Review
- Imaging the Influence of Red Blood Cell Docosahexaenoic Acid Status on the Expression of the 18 kDa Translocator Protein in the Brain: A [Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 3 institutions in 1 country.
Sung Won KimNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Corinde E WiersNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Ryan TylerNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Ehsan Shokri-KojoriNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.ORCID http://orcid.org/0000-0001-6846-3173
Yeon Joo JangNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Amna ZehraNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Clara FreemanNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Veronica RamirezNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Elsa LindgrenNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Gregg MillerNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Elizabeth A CabreraNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Tyler StoddenNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Min GuoNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Şükrü B DemiralNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Nancy DiazgranadosNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.ORCID http://orcid.org/0000-0002-7415-8455
Luke ParkMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA.
Jeih-San LiowMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA.
Victor PikeMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA.
Cheryl MorseMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA.
Leandro F VendruscoloNational Institute on Drug Abuse, NIH, Baltimore, MD, 21224, USA.
Robert B InnisMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA.
George F KoobNational Institute on Drug Abuse, NIH, Baltimore, MD, 21224, USA.
Dardo TomasiNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Gene-Jack WangNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Nora D VolkowNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA. nvolkow@nida.nih.gov.
National Institute on Alcohol Abuse and Alcoholism · USNational Institute of Mental Health · USNational Institute on Drug Abuse · US
Funding
Neurobiology of Substance Abuse and AddictionZIAAA000550 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI VOLKOW, NORA D. · 2009 to 2025
$115.1MPET Radiopharmaceutical SciencesZIAMH002793 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PIKE, VICTOR W · 2009 to 2025
$69.8MClinical Evaluation of PET RadiotracersZIAMH002852 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$48.6MTranslational Evaluation Of PET RadiotracersZIAMH002795 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$32.0MNIH HHS Y1AA-3009
Abstract
Neuroinflammation appears to contribute to neurotoxicity observed with heavy alcohol consumption. To assess whether chronic alcohol results in neuroinflammation we used PET and [
Indexed as
AcetamidesAlcoholismAnimalsBrainCarrier ProteinsCentral Nervous System DepressantsCholesterolEthanolFemaleHumansMaleMiddle AgedPositron-Emission TomographyProtein BindingPyridinesRadiopharmaceuticalsAcetamidesCarrier ProteinsCentral Nervous System DepressantsCholesterolEthanolN-(2-methoxybenzyl)-N-(4-phenoxypyridin-3-yl)acetamidePyridinesRadiopharmaceuticalsReceptors, GABAReceptors, GABA-ATSPO protein, humanTspo protein, rat
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.