Evidence map›Paper›PMID 29777174›Full record

ArticleScientific reports2018

How does blood regulate cerebral temperatures during hypothermia?

Stephen Blowers, Ian Marshall, Michael Thrippleton, Peter Andrews, Bridget Harris, Iain Bethune, Prashant Valluri

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Predicting brain temperature in humans using bioheat models: Progress and outlook.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Review
  5. Article
  6. Development of a Coherent Model for Radiometric Core Body Temperature Sensing.IEEE journal of electromagnetics, RF and microwaves in medicine and biology · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephen BlowersInstitute of Multiscale Thermofluids, School of Engineering, University of Edinburgh, Edinburgh, UK. S.Blowers@ed.ac.uk.
Ian MarshallCentre for Clinical Brain Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK.
Michael ThrippletonCentre for Clinical Brain Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK.
Peter AndrewsCentre for Clinical Brain Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK.
Bridget HarrisAnaesthesia, Critical Care and Pain Medicine, University of Edinburgh, Edinburgh, UK.
Iain BethuneSTFC Hartree Centre, Daresbury Laboratory, Warrington, UK.ORCID 0000-0003-0713-2084
Prashant ValluriInstitute of Multiscale Thermofluids, School of Engineering, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-4917-8283

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macro-modeling of cerebral blood flow can help determine the impact of thermal intervention during instances of head trauma to mitigate tissue damage. This work presents a bioheat model using a 3D fluid-porous domain coupled with intersecting 1D arterial and venous vessel trees. This combined vascular porous (VaPor) model resolves both cerebral blood flow and energy equations, including heat generated by metabolism, using vasculature extracted from MRI data and is extended using a tree generation algorithm. Counter-current flows are expected to increase thermal transfer within the brain and are enforced using either the vascular structure or flow reversal, represented by a flow reversal constant, C

Indexed as

Models, BiologicalAlgorithmsBody TemperatureBrainCerebrovascular CirculationHumansHypothermiaMagnetic Resonance ImagingPorosity

Identifiers

PMID29777174
PMCPMC5959945

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.