ArticleScientific reports2018
The modulation of acetic acid pathway genes in Arabidopsis improves survival under drought stress.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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34 citing papers in PubMed, 88 citations in OpenAlex.
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- Transcriptomic insights into drought response in wild Arachis relatives A. dardani and A. ipaënsis.BMC plant biology · 2025Article
- Dose and genotype dependent effects of foliar acetic acid on sweet corn under water deficit.Scientific reports · 2025Article
- BrHDA6 mediates nonhistone deacetylation of BrSOT12 to positively regulate downy mildew resistance inHorticulture research · 2025Article
- Chemical application improves stress resilience in plants.Plant molecular biology · 2025Review
- Comprehensive Analysis ofInternational journal of molecular sciences · 2024Article
- Acetic acid: a cheap but chief metabolic regulator for abiotic stress tolerance in plants.Stress biology · 2024Review
- Article
- Modulation of antioxidant defense and PSII components by exogenously applied acetate mitigates salinity stress in Avena sativa.Scientific reports · 2024Article
- Roles of Reactive Carbonyl Species (RCS) in Plant Response to Abiotic Stress.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Role of Acetic Acid and Nitric Oxide against Salinity and Lithium Stress in Canola (Plants (Basel, Switzerland) · 2023Article
- The Overexpression of Peanut (Plants (Basel, Switzerland) · 2023Article
- Simple and universal function of acetic acid to overcome the drought crisis.Stress biology · 2023Article
- Key Pathways and Genes ofPlants (Basel, Switzerland) · 2023Article
- Review
- Changes in Metal-Chelating Metabolites Induced by Drought and a Root Microbiome in Wheat.Plants (Basel, Switzerland) · 2023Article
- Article
- Comparative Metabolomic Studies of Siberian Wildrye (International journal of molecular sciences · 2022Article
- Ethanol treatment enhances drought stress avoidance in cassava (Manihot esculenta Crantz).Plant molecular biology · 2022Article
- Ethanol-Mediated Novel Survival Strategy against Drought Stress in Plants.Plant & cell physiology · 2022Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Arabidopsis histone deacetylase 6 (HDA6) mutant exhibits increased tolerance to drought stress by negatively regulating the expression of ALDH2B7 and PDC1. Therefore, it was logical to determine if transgenic Arabidopsis plants expressing PDC1 or ALDH2B7 using a suitable promoter would also exhibit tolerance to drought stress. An analysis of published microarray data indicated the up-regulation of the TSPO gene, which encodes an outer membrane tryptophan-rich sensory protein (TSPO), by drought stress. RT-qPCR, as well as GUS analysis of the promoter, confirmed the up-regulation of TSPO by drought stress in Arabidopsis roots and shoots. Thus, the TSPO promoter was used to drive drought-responsive expression of ALDH2B7 and PDC1. RT-qPCR analysis confirmed that the expression of PDC1 and ALDH2B7 was up-regulated, relative to WT plants, by drought stress in homozygous pTSPO-PDC1 and pTSPO-ALDH2B7 plant lines. pTSPO-ALDH2B7 and pTSPO-PDC1 transgenic lines showed prolonged survival under drought stress. Microarray analyses revealed transcriptomic changes related to metabolism in pTSPO-PDC1 plants, indicating that selective regulation of metabolism may occur; resulting in the acquisition of drought stress tolerance. These results confirmed that TSPO promoter can be used to elevate the expression of acetic acid biosynthesis pathway genes; ensuring prolonged survival under drought stress in Arabidopsis.
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