Trial reportScientific reports2018
A randomized controlled pilot trial of game-based training in individuals with spinocerebellar ataxia type 3.
Trial report in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- The Effectiveness of Virtual Reality-Based Interventions in Patients with Ataxic Conditions: A Systematic Review with Meta-Analysis.Sensors (Basel, Switzerland) · 2026Pooled it
- Effects of physiotherapy on degenerative cerebellar ataxia: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Pharmacological and non-pharmacological management of spinocerebellar ataxia: A systematic review.Journal of neurology · 2022Pooled it
- Balance and coordination training for patients with genetic degenerative ataxia: a systematic review.Journal of neurology · 2021Pooled it
- Investigating the Clinical Significance and Research Discrepancies of Balance Training in Degenerative Cerebellar Disease: A Systematic Review.American journal of physical medicine & rehabilitation · 2020Pooled it
- Home-based Hybrid Assistive Limb Lumbar Type Telerehabilitation in Spinocerebellar Ataxias: A Nonrandomized Open-label Trial.Cerebellum (London, England) · 2025Trial
- The Effects of Exergame on Postural Control in Individuals with Ataxia: a Rater-Blinded, Randomized Controlled, Cross-over Study.Cerebellum (London, England) · 2022Trial
- Impulsivity in cerebellar ataxia: an online, multidimensional assessment.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Sport performance in virtual worlds: a systematic review of sport simulation in neurological paralympic athletes and non-athlete populations.BMC sports science, medicine & rehabilitation · 2026Article
- Management of fragile X-associated tremor ataxia syndrome: a review for clinicians.Frontiers in neurology · 2026Review
- Treatment of primary adult-onset neurodegenerative cerebellar ataxias.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Review
- Co-occurrence of Wilson's Disease and Spinocerebellar Ataxia Type 3 in a Chinese Patient.Acta neurologica Belgica · 2025Article
- A Tailored Home-Based Training Program Improved Ataxia Severity and Participation in Adults With ARSACS.Cerebellum (London, England) · 2025Article
- Feasibility and Efficacy of Online Neuropsychological Assessment.Sensors (Basel, Switzerland) · 2023Article
- Remote assessment of cognition in Parkinson's disease and Cerebellar Ataxia: the MoCA test in English and Hebrew.Frontiers in human neuroscience · 2023Article
- Effectiveness and cost of integrated cognitive and balance training for balance and falls in cerebellar ataxia: a blinded two-arm parallel group RCT.Frontiers in neurology · 2023Article
- Rehabilitation in patients with cerebellar ataxias.Arquivos de neuro-psiquiatria · 2022Article
- Endurance exercise ameliorates phenotypes ineLife · 2022Article
- The protective role of exercise against age-related neurodegeneration.Ageing research reviews · 2022Review
- PONT: A Protocol for Online Neuropsychological Testing.Journal of cognitive neuroscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exergames are interactive video games used for exercise and may have therapeutic value in people with degenerative ataxia. The purpose of this study was to investigate potential effects of exergaming training on cerebellar ataxia in people with spinocerebellar ataxia type 3 (SCA3). Nine individuals with SCA3 were recruited and randomized to either exergaming or conventional group for a 4-week training period. The severity of ataxia was measured as the primary outcome by the Scale for the Assessment and Rating of Ataxia (SARA) and by the directional control of the limit of stability test. The secondary outcomes included upper-limb function and gait performance. After training, participants in the exergaming group had a significant decrease in the total SARA score and the gait-posture SARA subscore. Participants in the conventional training group did not show a significant improvement in selected outcome measures after the 4-week training period. No significant difference was found between groups for any of these measures. Our results suggested that the exergaming training program significantly decreased ataxia. These results support implementation of exergaming training for people with SCA3.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.