Evidence map›Paper›PMID 29777035›Full record

ArticleJournal of cell science2018

Septin-dependent remodeling of cortical microtubule drives cell reshaping during epithelial wound healing.

Asako Shindo, Anastasia Audrey, Maki Takagishi, Masahide Takahashi, John B Wallingford, Makoto Kinoshita

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Septin complexes: Ahead of the curve.Cytoskeleton (Hoboken, N.J.) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Two Septin Complexes Mediate Actin Dynamics During Cell Wound Repair.bioRxiv : the preprint server for biology · 2023
    Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Asako ShindoDivision of Biological Sciences, Department of Molecular Biology, Nagoya University Graduate School of Science, Nagoya 464-8602, Japan shindo.asako@f.mbox.nagoya-u.ac.jp kinoshita.makoto@c.mbox.nagoya-u.ac.jp.ORCID 0000-0002-3314-7151
Anastasia AudreyDivision of Biological Sciences, Department of Molecular Biology, Nagoya University Graduate School of Science, Nagoya 464-8602, Japan.
Maki TakagishiDepartment of Tumor Pathology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Masahide TakahashiDepartment of Tumor Pathology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
John B WallingfordDepartment of Molecular Biosciences, University of Texas at Austin, Austin 78712, USA.
Makoto KinoshitaDivision of Biological Sciences, Department of Molecular Biology, Nagoya University Graduate School of Science, Nagoya 464-8602, Japan shindo.asako@f.mbox.nagoya-u.ac.jp kinoshita.makoto@c.mbox.nagoya-u.ac.jp.ORCID 0000-0002-7592-2400
Nagoya University · JPThe University of Texas at Austin · US

Funding

Control of collective cell movement by planar cell polarity signalingR01GM104853 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI WALLINGFORD, JOHN B · 2015 to 2018
$1.3M
NIGMS NIH HHS R01 GM104853
6 · The paper itself

Abstract

Wounds in embryos heal rapidly through contraction of the wound edges. Despite well-recognized significance of the actomyosin purse string for wound closure, roles for other cytoskeletal components are largely unknown. Here, we report that the septin cytoskeleton cooperates with actomyosin and microtubules to coordinate circumferential contraction of the wound margin and concentric elongation of wound-proximal cells in

Indexed as

Epithelial CellsHumansMicrotubulesSeptinsWound HealingSeptinsCytoskeletonEmbryonic wound healingEpidermisXenopus laevis

Identifiers

PMID29777035
PMCPMC6031381
OpenAlexW2803862962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.