Evidence map›Paper›PMID 29777021›Full record

ArticleJournal of the American Society of Nephrology : JASN2018

Serum 6-Bromotryptophan Levels Identified as a Risk Factor for CKD Progression.

Adrienne Tin, Girish Nadkarni, Anne M Evans, Cheryl A Winkler, Erwin Bottinger, Casey M Rebholz, Mark J Sarnak, Lesley A Inker, Andrew S Levey, Michael S Lipkowitz and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Metabolomic signatures suggest altered bile acid and energy metabolism in CRB1- retinopathies.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Molecular pathways that drive diabetic kidney disease.The Journal of clinical investigation · 2023
    Review
  9. Article
  10. Clinical journal of the American Society of Nephrology : CJASN · 2020
    Article
  11. Article
  12. Article
  13. Metabolomics Research in Chronic Kidney Disease.Journal of the American Society of Nephrology : JASN · 2018 · on this map
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Adrienne TinDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; atin1@jhu.edu mgrams2@jhmi.edu.ORCID 0000-0002-4207-5866
Girish NadkarniDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Anne M EvansMetabolon, Inc., Morrisville, North Carolina.
Cheryl A WinklerBasic Research Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health and Leidos Biomedical Research, Frederick National Laboratory, Frederick, Maryland.
Erwin BottingerHasso Plattner Institute, Center of Digital Health, Potsdam, Germany.
Casey M RebholzDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Mark J SarnakWilliam B. Schwartz Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Maryland.ORCID 0000-0003-4927-6609
Lesley A InkerWilliam B. Schwartz Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Maryland.
Andrew S LeveyWilliam B. Schwartz Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Maryland.
Michael S LipkowitzDivision of Nephrology, Department of Medicine, Georgetown University, Washington, DC; and.
Lawrence J AppelDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Dan E ArkingMcKusick-Nathans Institute of Genetic Medicine and Department of Medicine, Division of Cardiology, and.
Josef CoreshDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Morgan E GramsDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; atin1@jhu.edu mgrams2@jhmi.edu.
Johns Hopkins University · USTufts Medical Center · USGeorgetown University · USHasso Plattner Institute · DEIcahn School of Medicine at Mount Sinai · USLeidos (United States) · USMetabolon (United States) · US

Funding

Genetics of Renal Disease in African AmericansZIABC010022 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WINKLER, CHERYL · 2009 to 2022
$8.9M
Multi-Omics and Chronic Kidney Disease: Correlation with HistologyR01DK108803 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Morgan Erika Grams, EUGENE P. RHEE · 2016 to 2026
$6.4M
Metabolomics for Identifying Biomarkers of Dietary Intake & Kidney Disease ProgressionK01DK107782 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI REBHOLZ, CASEY MARIE · 2016 to 2020
$778k
NIDDK NIH HHS K01 DK107782NIDDK NIH HHS R01 DK108803
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease ProgressionAdultAgedAllelesApolipoprotein L1BiomarkersBlack or African AmericanCohort StudiesFemaleGenotypeHumansMaleMiddle AgedMulticenter Studies as TopicRandomized Controlled Trials as TopicRenal Insufficiency, Chronic6-bromotryptophanAPOL1 protein, humanApolipoprotein L1BiomarkersTryptophanAASK (African American Study of Kidney Disease and Hypertension)chronic kidney diseaseend stage kidney diseaserenal function decline

Identifiers

PMID29777021
PMCPMC6050937
OpenAlexW2803161655

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.