Evidence map›Paper›PMID 29776545›Full record

ReviewAnalytica chimica acta2018

Evolution of clinical and environmental health applications of exhaled breath research: Review of methods and instrumentation for gas-phase, condensate, and aerosols.

M Ariel Geer Wallace, Joachim D Pleil

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Analytica chimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04564196 (Feasibility Study of the Collection of the Breath Metabolome From Healthy Parturients During Labor), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04564196 terminatednot on this mapstarted 2020, after this paper: background citation

Feasibility Study of the Collection of the Breath Metabolome From Healthy Parturients During Labor

TypeobservationalSponsorStanford UniversityRan2020 to 2023Enrolled53ConditionsLabor Onset and Length AbnormalitiesArmsBreath Sample
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Clinical utility of diagnostic biomarkers in malignant pleural mesothelioma: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2021
    Pooled it
  2. Exhaled Breath Analysis in Diagnosis of Malignant Pleural Mesothelioma: Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
  3. Observational
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  20. Rolosense: Mechanical detection of SARS-CoV-2 using a DNA-based motor.bioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

M Ariel Geer WallaceU.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, 109 T.W. Alexander Drive, Research Triangle Park, NC, 27711, USA. Electronic address: wallace.ariel@epa.gov.
Joachim D PleilU.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, 109 T.W. Alexander Drive, Research Triangle Park, NC, 27711, USA. Electronic address: pleil.joachim@epa.gov.

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

Human breath, along with urine and blood, has long been one of the three major biological media for assessing human health and environmental exposure. In fact, the detection of odor on human breath, as described by Hippocrates in 400 BC, is considered the first analytical health assessment tool. Although less common in comparison to contemporary bio-fluids analyses, breath has become an attractive diagnostic medium as sampling is non-invasive, unlimited in timing and volume, and does not require clinical personnel. Exhaled breath, exhaled breath condensate (EBC), and exhaled breath aerosol (EBA) are different types of breath matrices used to assess human health and disease state. Over the past 20 years, breath research has made many advances in assessing health state, overcoming many of its initial challenges related to sampling and analysis. The wide variety of sampling techniques and collection devices that have been developed for these media are discussed herein. The different types of sensors and mass spectrometry instruments currently available for breath analysis are evaluated as well as emerging breath research topics, such as cytokines, security and airport surveillance, cellular respiration, and canine olfaction.

Indexed as

AerosolsAnimalsBiomarkersBody FluidsBreath TestsChemistry Techniques, AnalyticalDogsEnvironmental HealthExhalationHumansMiceModels, AnimalSmellVolatile Organic CompoundsAerosolsBiomarkersVolatile Organic CompoundsAnalytical techniquesBiomarkersBreath researchExhaled breath aerosol (EBA)Exhaled breath condensate (EBC)Volatile organic compounds (VOCs)

Identifiers

PMID29776545
PMCPMC6082128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.