ReviewBMC infectious diseases2018
Primary bacterial ventriculitis in adults, an emergent diagnosis challenge: report of a meningoccal case and review of the literature.
Review in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 36 citations in OpenAlex.
- PrimaryInfectious diseases & clinical microbiology · 2026Article
- Meningococcal Disease in Older Adults: Challenges in Diagnosis and Management.Infectious diseases and therapy · 2026Review
- Community-Acquired Pneumococcal Ventriculitis as a Complication of Otogenic Pneumococcal Meningitis: A Case Report.Case reports in infectious diseases · 2026Article
- Article
- Escherichia coli Pyogenic Ventriculitis in an Infant Following Abdominal Surgery: A Rare Case Report.Cureus · 2025Article
- A retrospective study on the efficacy of neuro-endoscopic lavage compared to conventional antibiotic treatment in pyogenic ventriculitis.Neurosurgical review · 2025Article
- A Report of Primary Pyogenic Ventriculitis Caused byInfection and drug resistance · 2025Article
- Article
- Streptococcus intermedius causing primary bacterial ventriculitis in a patient with severe periodontitis - a case report.BMC neurology · 2024Article
- Primary Bacterial Ventriculitis caused by Staphylococcus warneri.Revista da Sociedade Brasileira de Medicina Tropical · 2023Article
- Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus's two-toed sloth (Choloepus didactylus).The Journal of veterinary medical science · 2022Article
- A Rare Case of Primary Pyogenic Ventriculitis in a Patient with Community-acquired Meningitis.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Article
- Invasive meningococcal disease in older adults in North America and Europe: is this the time for action? A review of the literature.BMC public health · 2022Review
- Primary ventriculitis presenting with isolated vestibular syndrome.Journal of neurology · 2021Article
- Recurrent primary pyogenic ventriculitis in an adult woman: a case report.BMC neurology · 2021Article
- Invasive infection due toClinical case reports · 2021Article
- Ventriculitis: A Severe Complication of Central Nervous System Infections.Open forum infectious diseases · 2021Article
- Male with Altered Mental Status.Clinical practice and cases in emergency medicine · 2021Article
- Pyogenic Ventriculitis Associated with Urosepsis: A Rare Case Report.European journal of case reports in internal medicine · 2020Article
- When a Stroke is not Just a Stroke:Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2020Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDefined by an infection of the ventricular system of the brain, ventriculitis is usually known as a health-care associated infection. In contrast, primary pyogenic ventriculitis complicating community-acquired meningitis is uncommon, and mainly described in infants. Only seven cases that have occured in adults have been found in the international literature. CASE PRESENTATION: We report here a new case due to Neisseria meningitidis occurring in an 85 year-old-man. The comparison with previous reports allows to drawn several conclusions: (i) cases occurred in relatively old adults (median age: 65 years); (ii) Streptococcus pneumoniae, N. meningitiditis and Staphylococcus aureus are the leading responsible pathogens; (iii) atypical clinical presentation seems the rule in which meningism often lacks; (iv) in absence of clinical or biological specific parameters, modern brain imaging such as magnetic resonance imaging with gadolinium enhancement is of utmost importance for the diagnosis, leading to anticipate an increase of the diagnosis in the near future, thanks to easier access to such exploration; (v) death or serious sequelae commonly occurred; (vi) prolonged antibiotic courses (6 weeks to 3 months) have been used, without strong rational. In the given case, the patient presented with a lack of meningeal irritation signs. The diagnosis was made by MRI considering a lasting confused state. A four-week antibiotic regimen was successful, combining two weeks of intravenous cefotaxime followed by two weeks of oral levofloxacin much easier to administrate and allowing early rehabilitation.
conclusionPrimary bacterial ventriculitis is a real diagnosis challenge. Larger indications of MRI for bacterial meningitis, particularly in cases with an atypical presentation or poor evolution would certainly increase the number of diagnosis.
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