Evidence map›Paper›PMID 29776315›Full record

ArticleRedox report : communications in free radical research2018

Aerobic training reduces oxidative stress in skeletal muscle of rats exposed to air pollution and supplemented with chromium picolinate.

Bruna Marmett, Ramiro Barcos Nunes, Kellen Sábio de Souza, Pedro Dal Lago, Cláudia Ramos Rhoden

Open access · goldAbstract read
In one paragraph

Article in Redox report : communications in free radical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bruna Marmetta Laboratory of Atmospheric Pollution, Graduate Program in Health Science , Federal University of Health Sciences of Porto Alegre (UFCSPA) , Porto Alegre , Brazil.ORCID http://orcid.org/0000-0002-2982-0323
Ramiro Barcos Nunesb Research Department , Sul-Rio-Grandense Federal Institute of Education, Science and Technology , Gravataí , Brazil.
Kellen Sábio de Souzaa Laboratory of Atmospheric Pollution, Graduate Program in Health Science , Federal University of Health Sciences of Porto Alegre (UFCSPA) , Porto Alegre , Brazil.
Pedro Dal Lagoc Laboratory of Experimental Physiology , Federal University of Health Sciences of Porto Alegre (UFCSPA) , Porto Alegre , Brazil.ORCID http://orcid.org/0000-0001-9907-7689
Cláudia Ramos Rhodena Laboratory of Atmospheric Pollution, Graduate Program in Health Science , Federal University of Health Sciences of Porto Alegre (UFCSPA) , Porto Alegre , Brazil.ORCID http://orcid.org/0000-0002-3099-9375
Universidade Federal de Ciências da Saúde de Porto Alegre · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this study was to investigate the effects of chromium picolinate (CrPic) supplementation associated with aerobic exercise using measures of oxidative stress in rats exposed to air pollution.

methodsSixty-one male Wistar rats were divided into eight groups: residual oil fly ash (ROFA) exposure and sedentary (ROFA-SED); ROFA exposure, sedentary and supplemented (ROFA-SED-CrPic); ROFA exposure and trained (ROFA-AT); ROFA exposure, supplemented and trained (ROFA-AT-CrPic); sedentary (Sal-SED); sedentary and supplemented (Sal-SED-CrPic); trained (Sal-AT); and supplemented and trained (Sal-AT-CrPic). Rats exposed to ROFA (air pollution) received 50 µg of ROFA daily via intranasal instillation. Supplemented rats received CrPic (1 mg/kg/day) daily by oral gavage. Exercise training was performed on a rat treadmill (5×/week). Oxidative parameters were evaluated at the end of protocols.

resultsTrained groups demonstrated lower gain of body mass (P < .001) and increased exercise tolerance (P < .0001). In the gastrocnemius, trained groups demonstrated increased SOD activity (P < .0001) and decrease levels of TBARS (P = .0014), although CAT activity did not differ among groups (P = .4487).

conclusionAir pollution exposure did not lead to alterations in oxidative markers in lungs and heart, and exercise training was responsible for decreasing oxidative stress of the gastrocnemius.

Indexed as

AerobiosisAir PollutionAnimalsMaleMuscle, SkeletalOxidative StressPhysical Conditioning, AnimalPicolinic AcidsRatsRats, WistarSuperoxide DismutaseThiobarbituric Acid Reactive Substancespicolinic acidPicolinic AcidsSuperoxide DismutaseThiobarbituric Acid Reactive SubstancesAir pollutionchromium tripicolinatedietary supplementsexerciseoxidative stress

Identifiers

PMID29776315
PMCPMC6748694
OpenAlexW2803550883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.