Evidence map›Paper›PMID 29775871›Full record

ArticleChild abuse & neglect2018

Associations between abuse/neglect and ADHD from childhood to young adulthood: A prospective nationally-representative twin study.

Adi Stern, Jessica Agnew-Blais, Andrea Danese, Helen L Fisher, Sara R Jaffee, Timothy Matthews, Guilherme V Polanczyk, Louise Arseneault

Open access · hybridAbstract readTwin Study
In one paragraph

Article in Child abuse & neglect, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 4 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 4 syntheses or guidelines pooled it, 115 citations in OpenAlex.

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  7. Early life stress induces sex-specific changes in cognitive and affective behavior associated with disrupted noradrenergic physiology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  8. Cumulative Adverse Childhood Experiences and Multiple Neurodevelopmental Disorders in Children and Adolescents: A Population-Based Study.Stress and health : journal of the International Society for the Investigation of Stress · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Adi SternSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom. Electronic address: adi.stern@kcl.ac.uk.
Jessica Agnew-BlaisSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom. Electronic address: jessica.agnew-blais@kcl.ac.uk.
Andrea DaneseSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom. Electronic address: andrea.danese@kcl.ac.uk.
Helen L FisherSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom. Electronic address: helen.2.fisher@kcl.ac.uk.
Sara R JaffeeDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: srjaffee@psych.upenn.edu.
Timothy MatthewsSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom. Electronic address: timothy.matthews@kcl.ac.uk.
Guilherme V PolanczykUniversity of São Paulo, São Paulo, Brazil. Electronic address: gvp.ez@terra.com.br.
Louise ArseneaultSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom. Electronic address: louise.arseneault@kcl.ac.uk.
King's College London · GBUniversidade de São Paulo · BRUniversity of Pennsylvania · US

Funding

Medical Research Council G1002190Medical Research Council MR/P014100/1
6 · The paper itself

Abstract

Child maltreatment has consistently been found to be associated with attention deficit/hyperactivity disorder (ADHD). However, the robustness of this association and the direction of the link between maltreatment and ADHD remain unclear. We used data from the Environmental Risk (E-Risk) Longitudinal Twin Study, a cohort of 2232 British twins, to investigate the associations between exposure to abuse/neglect and ADHD in childhood and in young adulthood, and to test their robustness and specificity. We also aimed to test longitudinal associations between abuse/neglect and ADHD from childhood to young adulthood, controlling for confounders. Results indicated strong associations between abuse/neglect and ADHD in childhood and also in young adulthood. In childhood, the association was concentrated among children with comorbid conduct disorder. Longitudinal analyses showed that childhood ADHD predicted abuse/neglect in later years. This association was again concentrated among individuals with comorbid conduct disorder. Abuse/neglect in childhood was not associated with later ADHD in young adulthood after adjusting for childhood ADHD. Our study does not provide support of a causal link between child abuse/neglect and adult ADHD but highlights the possibility of a long-term effect of disruptive behaviors on the risk for experiencing abuse/neglect. These findings emphasize the need for clinicians treating people with ADHD, especially those with comorbid conduct disorder, to be aware of their increased risk for experiencing abuse/neglect. Interventions aimed at reducing risks of abuse/neglect should also focus on the environment of individuals with disruptive behaviors.

Indexed as

AdolescentAdultAdult Survivors of Child AbuseAttention Deficit Disorder with HyperactivityChildChild, PreschoolCohort StudiesEnglandFemaleHumansLongitudinal StudiesMaleProblem BehaviorProspective StudiesYoung AdultAbuse/neglectChildhood ADHDConduct disorderLongitudinal designMaltreatmentYoung adult ADHD

Identifiers

PMID29775871
PMCPMC6013278
OpenAlexW2803240020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.