ArticleMolecular cell2018
At Long Last, a C-Terminal Bookend for the Ubiquitin Code.
Article in Molecular cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Emerging Roles of Non-proteolytic Ubiquitination in Tumorigenesis.Frontiers in cell and developmental biology · 2022Review
- Nuclear βII-Tubulin and its Possible Utility in Cancer Diagnosis, Prognosis and Treatment.Frontiers in cell and developmental biology · 2022Article
- End-Binding E3 Ubiquitin Ligases Enable Protease Signaling.ACS chemical biology · 2021Review
- Molecular basis for ubiquitin ligase CRL2Nature chemical biology · 2021Article
- Molecular basis for arginine C-terminal degron recognition by Cul2Nature chemical biology · 2021Article
- Degradation of proteins with N-terminal glycine.Nature structural & molecular biology · 2019Article
- N-degron and C-degron pathways of protein degradation.Proceedings of the National Academy of Sciences of the United States of America · 2019Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ubiquitin-proteasome system controls the stability of myriad protein substrates via short sequence motifs called degrons. Studies by Koren et al. (2018) and Lin et al. (2018) have uncovered a broad new class of degrons located at the extreme C terminus of substrates.
Indexed as
Identifiers
29775575What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.