ReviewThe world journal of men's health2019
Varicocele and Testicular Pain: A Review.
Review in The world journal of men's health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03835143 (the Effect of Sub-inguinal Varicocelectomy in Patients Complaining of Orchialgia With Normal Semen Analysis), which is not on this map. Cited by 50 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
the Effect of Sub-inguinal Varicocelectomy in Patients Complaining of Orchialgia With Normal Semen Analysis
Who cites it
50 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Varicocele repair for severe oligoasthenoteratozoospermia: Scoping review of published guidelines, and systematic review of the literature.Arab journal of urology · 2025Pooled it
- Varicocele repair in improving spermatozoa, follicle-stimulating hormone, and luteinizing hormone parameters in infertile males with azoospermia: a systematic review and meta-analysis.Asian journal of andrology · 2024Pooled it
- Ultrasound evaluation of varicoceles: systematic literature review and rationale of the ESUR-SPIWG Guidelines and Recommendations.Journal of ultrasound · 2020Pooled it
- Ultrasound evaluation of varicoceles: guidelines and recommendations of the European Society of Urogenital Radiology Scrotal and Penile Imaging Working Group (ESUR-SPIWG) for detection, classification, and grading.European radiology · 2020Guideline
- Does Sperm DNA Fragmentation Index Continuously Decrease Over Time After Varicocelectomy in Varicocele-Induced Infertility? A Systematic Review and Meta-Analysis.American journal of men's healthPooled it
- Ultrasound maximum vein diameter contextualizes testicular asymmetry in adolescent varicocele.International urology and nephrology · 2026Article
- Association between varicocele and hemorrhoidal disease in men presenting with groin pain: a retrospective comparative study.BMC urology · 2026Article
- Testicular vein syndrome: hydronephrosis secondary to ureteral compression-a case report.Journal of medical case reports · 2026Article
- Scrotal Pain Alters Doppler Findings in Varicocele: A Prospective Evaluation.Journal of clinical medicine · 2026Article
- Beyond venous dilatation: Nutcracker syndrome and Its Unique Hemodynamic Signature in Adolescent Varicocele.World journal of urology · 2025Article
- Article
- Recent Guidelines and Perspectives for Varicocele: A Clinical Consensus and Recommendations from the Korean Society for Sexual Medicine and Andrology.The world journal of men's health · 2025Review
- Paediatric Varicocele Embolisation: Clinical Experience, Insights and Long Term Clinical Outcomes Over 14 Years at a Tertiary Centre-A Cohort Study.Journal of medical imaging and radiation oncology · 2025Article
- A fifteen-year retrospective analysis of varicocele embolization: evaluating success, recurrence rates and embolic agents.CVIR endovascular · 2025Article
- From imaging techniques to laboratory tests: a multimodal stratification for varicocele-associated decreased semen quality.Basic and clinical andrology · 2025Review
- Long-term efficacy and catheter choice in male varicocele embolization using NBCA-MS glue.International urology and nephrology · 2025Article
- The involvement of TRPV1 in the apoptosis of spermatogenic cells in the testis of mice with cryptorchidism.Cell death discovery · 2025Article
- Clinical evaluation and comprehensive management strategies for adolescent varicocele.Pediatric surgery international · 2025Review
- Challenging cases of adherent periarterial vein during subinguinal Fisch technique and subinguinal micro-varicocelecotmy and sclerotherapy: a prospective comparative study.Basic and clinical andrology · 2025Article
- Efficiency and safety of microscopic cluster ligation of the internal spermatic veins: A prospective matched case-control study.Central European journal of urology · 2025Article
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2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Varicocele is the dilatation of the scrotal portion of pampiniform plexus and the internal spermatic venous system. About 15% of men suffer from scrotal varicocele and 2% to 10% of them complain of pain. The probable mechanisms for pain include compression of the surrounding neural fibers by the dilated venous complex, elevated testicular temperature, increased venous pressure, hypoxia, oxidative stress, hormonal imbalances, and the reflux of toxic metabolites of adrenal or renal origin. Testicular pain associated with varicoceles is typically described as a dull, aching, or throbbing pain in the testicle, scrotum, or groin; rarely, it can be acute, sharp, or stabbing. The management of testicular pain associated with varicocele starts with a conservative, non-surgical approach and a period of observation. Varicocelectomy in carefully selected candidates with clinically palpable varicocele resolves nearly 80% of all cases of testicular pain. Microsurgical techniques for varicocelectomy have gained popularity with minimal complication rates and favorable outcomes. The grade of varicocele, the nature and duration of pain, body mass index, prior conservative management, and the type of surgical method used, are predictors for the success of varicocelectomy.
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