Observational studyClinical cardiology2018
Influence of sex and pregnancy on survival in patients admitted with heart failure: Data from a prospective multicenter registry.
Observational study in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Development a nomogram prognostic model for survival in heart failure patients based on the HF-ACTION data.BMC medical informatics and decision making · 2024Article
- Pregnancy, Reproductive Factors, and Female Heart Failure Risk and Outcomes.Current heart failure reports · 2024Review
- Italian Association of Hospital Cardiologists Position Paper 'Gender discrepancy: time to implement gender-based clinical management'.European heart journal supplements : journal of the European Society of Cardiology · 2024Article
- Ischemic cardiomyopathy: epidemiology, pathophysiology, outcomes, and therapeutic options.Heart failure reviews · 2024Review
- Heart Failure in the Elderly: the Role of Biological and Sociocultural Aspects Related to Sex.Current heart failure reports · 2023Review
- Coronary Artery Disease and Prognosis of Heart Failure with Reduced Ejection Fraction.Journal of clinical medicine · 2023Article
- Sudden Death in Men Versus Women with Heart Failure.Current heart failure reports · 2023Review
- Factors Influencing Functional Coronary Artery Ischemia: A Gender-Specific Predictive Model.Risk management and healthcare policy · 2023Article
- Individual variability in human urinary metabolites identifies age-related, body mass index-related, and sex-related biomarkers.Molecular genetics & genomic medicine · 2021Article
- Sex, Lies, and Coronary Artery Disease.Journal of clinical medicine · 2021Article
- Ischemic Etiology and Prognosis in Men and Women with Acute Heart Failure.Journal of clinical medicine · 2021Article
- Sex Influence on Heart Failure Prognosis.Frontiers in cardiovascular medicine · 2020Review
- Influence of sex and pregnancy on survival in patients admitted with heart failure: Data from a prospective multicenter registry.Clinical cardiology · 2018Observational
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFemale sex is an independent predictor of better survival in patients with heart failure (HF), but the mechanism of this association is unknown. On the other hand, pregnancies have a strong influence on the cardiovascular system. HYPOTHESIS: Sex and previous gestations might have a prognostic impact on 1-year mortality in patients admitted with HF.
methodsWe conducted an observational, prospective, consecutive, multicenter registry of 1831 patients (756 females [41.2%]) admitted with HF.
resultsFemales had a more advanced age (75.2 ±11.4 vs 70.4 ±12.2 years), less ischemic heart disease (167 [25.3%] vs 446 [47.3%]), and higher left ventricular ejection fraction (52.0% ±16.6% vs 41.1% ±17.0%) than did men (all P values <0.001). During 1-year follow-up, 373 (20.4%) patients died (151 females and 222 males). Female sex was an independent predictor for survival (hazard ratio: 0.79, 95% confidence interval: 0.64-0.98, P = 0.03). In 504 women (65.9%), the exact number of previous pregnancies could be determined; 62 women (12.3%) had no previous pregnancies, 288 (57.1%) women had 1 or 2 pregnancies, and 154 women (30.6%) had ≥3 pregnancies. We found an association between the number of previous gestations and better survival (hazard ratio: 0.878, 95% confidence interval: 0.773-0.997, P = 0.045).
conclusionsIn patients admitted with HF, female sex and the number of previous pregnancies are independently associated with better 1-year survival.
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