ArticlePediatric nephrology (Berlin, Germany)2018
Combining GFR estimates from cystatin C and creatinine-what is the optimal mix?
Article in Pediatric nephrology (Berlin, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Early and late adverse renal effects after potentially nephrotoxic treatment for childhood cancer.The Cochrane database of systematic reviews · 2019Pooled it
- Gold Standard GFR measurement and GFR estimation in pediatric oncology - indications and limitations.Pediatric nephrology (Berlin, Germany) · 2026Review
- Direct Measurement of GFR: Who, When, and How?: A Practical Approach Emphasizing Iohexol Plasma Clearance.Journal of the American Society of Nephrology : JASN · 2026Review
- Review
- Correlations between serum kidney injury molecule-1, cystatin C and immunosuppressants: A cross-sectional study of renal transplant patients in Bahrain.Journal of biomedical research · 2024Article
- The complexity of kidney disease and diagnosing it - cystatin C, selective glomerular hypofiltration syndromes and proteome regulation.Journal of internal medicine · 2023Review
- Creatinine-based GFR-estimating equations in children with overweight and obesity.Pediatric nephrology (Berlin, Germany) · 2022Observational
- Estimating Renal Function Following Lung Transplantation.Journal of clinical medicine · 2022Article
- Dimethylarginines in Children after Anti-Neoplastic Treatment.Medicina (Kaunas, Lithuania) · 2022Article
- Carboplatin Dosing in Children Using Estimated Glomerular Filtration Rate: Equation Matters.Cancers · 2021Article
- Assessment of kidney function: clinical indications for measured GFR.Clinical kidney journal · 2021Review
- Obesity Facts and Their Influence on Renal Function Across the Life Span.Frontiers in medicine · 2021Review
- Area under the Curve-Based Dosing of Vancomycin in Critically Ill Patients Using 6-Hour Urine Creatinine Clearance Measurement.Critical care research and practice · 2020Article
- Validation of standardized creatinine and cystatin C GFR estimating equations in a large multicentre European cohort of children.Pediatric nephrology (Berlin, Germany) · 2019Article
- Estimating glomerular filtration rate in children: evaluation of creatinine- and cystatin C-based equations.Pediatric nephrology (Berlin, Germany) · 2019Observational
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCombining estimated glomerular filtration rate (eGFR) equations based on creatinine and cystatin C has been shown to improve the accuracy of GFR estimation. This study aims to optimize this strategy for height-independent GFR estimation in children.
methodsRetrospective study of 408 inulin clearance tests with simultaneous International Federation of Clinical Chemistry-calibrated measurements of creatinine, cystatin C, and urea in children (mean age 12.5 years, GFR 91.2 ml/min/1.73m
resultsMean
conclusionsIn the absence of height data, the optimal strategy for estimating GFR in children is by using the geometric mean of FASage and FAScys. When there is large disagreement between the two, weighted means based on diagnosis improve accuracy.
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Registered trials
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