ArticleLa Radiologia medica2018
Analysis of three ultrasound elastography techniques for grading liver fibrosis in patients with chronic hepatitis B.
Article in La Radiologia medica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 22 citations in OpenAlex.
- Noninvasive prediction of high-risk esophageal varices by spleen and liver stiffness measurements using sound touch elastography.Liver research (Beijing, China) · 2025Article
- Ultrasound—New Techniques Are Extending the Applications.Deutsches Arzteblatt international · 2023Article
- Effects of Confounding Factors on Liver Stiffness in Two-Dimensional Shear Wave Elastography in Beagle Dogs.Frontiers in veterinary science · 2022Article
- Shear wave elastography and transient elastography in HCV patients after direct-acting antivirals.La Radiologia medica · 2021Article
- Shear wave-based sound touch elastography in liver fibrosis assessment for patients with autoimmune liver diseases.Quantitative imaging in medicine and surgery · 2021Article
- Narrative review of multiparametric ultrasound in parotid gland evaluation.Gland surgery · 2020Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEvaluation of liver fibrosis is important to assess prognosis and guide the treatment for chronic hepatitis B.
objectiveTo analyze and compare transient, point, and two-dimensional (2D) shear wave elastography techniques in grading the liver fibrosis.
methodsBased on the severity of liver inflammation and fibrosis (Scheuer criteria), 158 patients with chronic hepatitis B were assigned into group 1 (either G or S classification < 2) or group 2 (either G or S classification ≥ 2). Group 2 patients commonly require anti-viral treatment. All patients received transient (FibroScan), point (STQ), and 2D (STE) elastography examinations. Receiver operating characteristic curves were calculated from three elastography techniques in individual or in combination.
resultsA total of 158 patients were enrolled into the study, with 39.2% (62) female and mean age of 42.8 (standard deviation 19.1) years old. Transient elastography could not differentiate between group 1 and group 2 patients (P = 0.12), whereas point and 2D elastography examinations could distinguish patients in group 1 from group 2 (P < 0.01 for both STQ and STE). Administration of combined three elastography techniques showed the best diagnostic accuracy (90.1%) for liver fibrosis, which was confirmed with hepatic biopsy examination.
conclusionPoint and 2D elastography were superior to transient elastography to detect liver fibrosis and guide clinical anti-viral treatment. Analysis of combined transient, point, and 2D elastography techniques showed the better diagnostic accuracy for liver fibrosis.
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