ArticleEuropean journal of breast health2018
Dual-Phase ADC Modelling of Breast Masses in Diffusion-Weighted Imaging: Comparison with Histopathologic Findings.
Article in European journal of breast health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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4 authors.
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Abstract
objectiveTo investigate the diagnostic value of dual-phase apparent diffusion coefficient (ADC) compared to traditional ADC values in quantitative diffusion-weighted imaging (DWI) for differentiating between benign and malignant breast masses. MATERIALS AND
methodsDiffusion-weighted images of pathologically confirmed 88 benign and 85 malignant lesions acquired using a 3.0T MR scanner were analyzed. Small region-of-interests focusing on the highest signal intensity of lesions were used. Lesion ADC estimates were obtained separately from all b-value images (ADC; b=50, 400 and 800s/mm
resultsStrong positive correlation is observable between ADC and all dpADCs (ρ=0.80-1.00). Differences in ADC and dpADCs between the benign and the malignant lesions are all significant (p<0.05). In detecting malignancy, traditional lesion ADC provides a good performance (AUC=89.9%) however dpADC
conclusionDual-phase ADC modelling may improve the accuracy in breast cancer diagnosis using DWI. Further prospective studies are needed to justify its benefit in clinical setting.
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