Evidence map›Paper›PMID 29774031›Full record

ArticleFrontiers in immunology2018

IL-10 Producing B Cells Ability to Induce Regulatory T Cells Is Maintained in Rheumatoid Arthritis.

Julie Mielle, Rachel Audo, Michael Hahne, Laurence Macia, Bernard Combe, Jacques Morel, Claire Daien

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02615951 (Characterization of B Regulatory), which is not on this map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02615951 nacompletednot on this map

Characterization of B Regulatory (Breg) Cells in Healthy Subjects and in Rheumatoid Arthritis (RA)

TypeinterventionalSponsorUniversity Hospital, MontpellierRan2015 to 2018Enrolled100ConditionsHealthy Volunteers, Arthritis, RheumatoidArmsblood sampling
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Pro-Resolving Macrophage-Induced IL-35International journal of molecular sciences · 2025
    Article
  7. Expansion of B10 cellsInternational journal of molecular medicine · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. New Chromones fromPlants (Basel, Switzerland) · 2022
    Article
  18. Propionic acid regulates immune tolerant properties in B Cells.Journal of cellular and molecular medicine · 2022
    Article
  19. Frontiers in immunology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Julie MielleMontpellier University, Montpellier, France.
Rachel AudoMontpellier University, Montpellier, France.
Michael HahneMontpellier University, Montpellier, France.
Laurence MaciaCharles Perkins Centre, Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney, NSW, Australia.
Bernard CombeMontpellier University, Montpellier, France.
Jacques MorelMontpellier University, Montpellier, France.
Claire DaienMontpellier University, Montpellier, France.
Université de Montpellier · FRCentre National de la Recherche Scientifique · FRInstitut de Génétique Moléculaire de Montpellier · FRUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite growing evidence highlighting the relevance of increasing IL-10-producing B cells (B10

Indexed as

AdultAgedArthritis, RheumatoidB-Lymphocytes, RegulatoryCell DifferentiationFemaleHumansInterleukin-10Lymphocyte ActivationMaleMiddle AgedOligodeoxyribonucleotidesT-Lymphocytes, Helper-InducerT-Lymphocytes, RegulatoryTumor Necrosis Factor-alphaIL10 protein, humanInterleukin-10OligodeoxyribonucleotidesTNF protein, humanTumor Necrosis Factor-alphaautoimmunityB10interleukin 10programmed death-ligand 2regulatory B cellrheumatoid arthritis

Identifiers

PMID29774031
PMCPMC5943500
OpenAlexW2802634531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.