Evidence map›Paper›PMID 29774028›Full record

ArticleFrontiers in immunology2018

NLRP3 Inflammasome and Caspase-1/11 Pathway Orchestrate Different Outcomes in the Host Protection Against

Augusto F Paroli, Patricia V Gonzalez, Cintia Díaz-Luján, Luisina I Onofrio, Alfredo Arocena, Roxana C Cano, Eugenio A Carrera-Silva, Susana Gea

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Theracurmin Modulates Cardiac Inflammation in Experimental Model ofTropical medicine and infectious disease · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Antiparasitic Effect of Stilbene and Terphenyl Compounds againstPharmaceuticals (Basel, Switzerland) · 2021
    Article
  12. Review
  13. Review
  14. Review
  15. Frontiers in cellular and infection microbiology · 2021
    Article
  16. Review
  17. Article
  18. The Beneficial Roles of SIRT1 in Drug-Induced Liver Injury.Oxidative medicine and cellular longevity · 2019
    Review
  19. Review
  20. Limited Foxp3Frontiers in immunology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Augusto F ParoliCentro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI - CONICET), Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Patricia V GonzalezCentro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI - CONICET), Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Cintia Díaz-LujánInstituto de Biología Celular, Facultad de Medicina, Universidad Nacional de Córdoba, Córdoba, Argentina.
Luisina I OnofrioCentro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI - CONICET), Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Alfredo ArocenaCentro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI - CONICET), Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Roxana C CanoCentro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI - CONICET), Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Eugenio A Carrera-SilvaInstituto de Medicina Experimental (IMEX-CONICET), Academia Nacional de Medicina, Buenos Aires, Argentina.
Susana GeaCentro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI - CONICET), Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Universidad Nacional de Córdoba · ARConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection with protozoan parasite

Indexed as

Acute DiseaseAnimalsCaspase 1CaspasesCaspases, InitiatorChagas DiseaseCytokinesInflammasomesInterleukin-1betaLiverMacrophagesMaleMiceMice, Inbred C57BLMice, KnockoutNLR Family, Pyrin Domain-Containing 3 ProteinCasp4 protein, mouseCaspase 1CaspasesCaspases, InitiatorCytokinesInflammasomesInterleukin-1betaNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseReactive Oxygen SpeciesTransaminasescaspase-1/11inflammasomelivermacrophagesNLRP3Trypanosoma cruzi, Chagas disease

Identifiers

PMID29774028
PMCPMC5944318
OpenAlexW2800398697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.