Evidence map›Paper›PMID 29774011›Full record

ArticleFrontiers in microbiology2018

Metabolomics Analysis of the Toxic Effects of the Production of Lycopene and Its Precursors.

April M Miguez, Monica P McNerney, Mark P Styczynski

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Metabolic Dynamics inACS synthetic biology · 2021
    Article
  6. Metabolic EngineeringMolecules (Basel, Switzerland) · 2020
    Review
  7. Article
  8. Metabolic Profiling ofIndustrial & engineering chemistry research · 2019
    Article
  9. Article
  10. Rewiring of Metabolic Network inFrontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

April M MiguezSchool of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, United States.
Monica P McNerneySchool of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, United States.
Mark P StyczynskiSchool of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, United States.
Georgia Institute of Technology · US

Funding

Modeling metabolic dynamics and regulation in biological systemsR35GM119701 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI STYCZYNSKI, MARK PHILIP-WALTER · 2016 to 2020
$1.6M
Synthetic biology-based detection of micronutrients with minimal equipmentR01EB022592 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI STYCZYNSKI, MARK PHILIP-WALTER · 2017 to 2020
$1.4M
NIBIB NIH HHS R01 EB022592NIGMS NIH HHS R35 GM119701
6 · The paper itself

Abstract

Using cells as microbial factories enables highly specific production of chemicals with many advantages over chemical syntheses. A number of exciting new applications of this approach are in the area of precision metabolic engineering, which focuses on improving the specificity of target production. In recent work, we have used precision metabolic engineering to design lycopene-producing

Indexed as

biosensorsgas chromatography-mass spectrometrylycopenemetabolomicsmevalonateprecision metabolic engineering

Identifiers

PMID29774011
PMCPMC5944366
OpenAlexW2795391175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.