ArticleNature communications2018
Iodine-catalyzed diazo activation to access radical reactivity.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- On-DNA photochemical methods for expanding DNA-encoded library (DEL) chemical space.RSC medicinal chemistry · 2026Review
- Article
- Recent Advances in Iodine-Mediated Radical Reactions.Advanced synthesis & catalysis · 2025Article
- Nickel-Catalyzed Branched Hydroalkylation of Alkenes with Diazo Compounds.Journal of the American Chemical Society · 2025Article
- Organophotocatalyst Enabled Deoxycyclopropanation of Alcohols.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Visible Light-Induced Reactions of Diazo Compounds and Their Precursors.Chemical reviews · 2024Review
- Rejuvenation of dearomative cycloaddition reactionsChemical science · 2023Review
- Electrochemical Cycloaddition Reactions of Alkene Radical Cations: A Route toward Cyclopropanes and Cyclobutanes.Organic letters · 2023Article
- Intermolecular Organophotocatalytic Cyclopropanation of Unactivated Olefins.Journal of the American Chemical Society · 2023Article
- Synthesis of Vicinal Carbocycles by Intramolecular Nickel-Catalyzed Conjunctive Cross-Electrophile Coupling Reaction.Organic letters · 2022Article
- Photons or Electrons? A Critical Comparison of Electrochemistry and Photoredox Catalysis for Organic Synthesis.Chemical reviews · 2022Review
- Visible Light Induced Brønsted Acid Assisted Pd-Catalyzed Alkyl Heck Reaction of Diazo Compounds and N-Tosylhydrazones.Angewandte Chemie (International ed. in English) · 2022Article
- Gold-Catalyzed Synthesis of Small Rings.Chemical reviews · 2021Article
- Boosting cancer therapy efficiencyChemical science · 2021Article
- Visible light-induced photocatalytic C-H ethoxycarbonylmethylation of imidazoheterocycles with ethyl diazoacetate.RSC advances · 2020Article
- Hexafluoroisopropanol-Promoted Disulfidation and Diselenation of Alkyne, Alkene, and Allene.Organic letters · 2020Article
- Diazo Activation with Diazonium Salts: Synthesis of Indazole and 1,2,4-Triazole.Organic letters · 2020Article
- Photocatalyzed Diastereoselective Isomerization of Cinnamyl Chlorides to Cyclopropanes.Journal of the American Chemical Society · 2020Article
- Metal-free synthesis of phosphinoylchroman-4-ones via a radical phosphinoylation-cyclization cascade mediated by KBeilstein journal of organic chemistry · 2020Article
- A transition-metal-free & diazo-free styrene cyclopropanation.Chemical science · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Transition-metal-catalyzed diazo activation is a classical way to generate metal carbene, which are valuable intermediates in synthetic organic chemistry. An alternative iodine-catalyzed diazo activation is disclosed herein under either photo-initiated or thermal-initiated conditions, which represents an approach to enable carbene radical reactivity. This metal-free diazo activation strategy were successfully applied into olefin cyclopropanation and epoxidation, and applying this method to pyrrole synthesis under thermal-initiated conditions further demonstrates the unique reactivity using this method over typical metal-catalyzed conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.