Evidence map›Paper›PMID 29773666›Full record

ArticleScience (New York, N.Y.)2018

Ancient genomes document multiple waves of migration in Southeast Asian prehistory.

Mark Lipson, Olivia Cheronet, Swapan Mallick, Nadin Rohland, Marc Oxenham, Michael Pietrusewsky, Thomas Oliver Pryce, Anna Willis, Hirofumi Matsumura, Hallie Buckley and 24 more

Open access · greenAbstract readHistorical Article
In one paragraph

Article in Science (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed, 2 pooled it
29.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 2 syntheses or guidelines pooled it, 436 citations in OpenAlex.

  1. Estimating human mobility in Holocene Western Eurasia with large-scale ancient genomic data.Proceedings of the National Academy of Sciences of the United States of America · 2023
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  16. Global patterns of natural selection inferred using ancient DNA.bioRxiv : the preprint server for biology · 2026
    Article
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  20. Evolutionary histories of functional mutations during the domestication and spread ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article

84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors at 18 institutions in 13 countries.

Mark LipsonDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA. mlipson@genetics.med.harvard.edu ron.pinhasi@univie.ac.at reich@genetics.med.harvard.edu.ORCID 0000-0001-5346-9329
Olivia CheronetDepartment of Anthropology, University of Vienna, 1090 Vienna, Austria.ORCID 0000-0001-6760-1204
Swapan MallickDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Nadin RohlandDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Marc OxenhamSchool of Archaeology and Anthropology, Australian National University, Canberra, ACT 0200, Australia.
Michael PietrusewskyDepartment of Anthropology, University of Hawai'i at Mānoa, Honolulu, Hawai'i 96822, USA.
Thomas Oliver PryceCentre National de la Recherche Scientifique, 75016 Paris, France.ORCID 0000-0002-7290-141X
Anna WillisCollege of Arts, Society and Education, James Cook University, Townsville, Queensland 4811, Australia.ORCID 0000-0002-3265-862X
Hirofumi MatsumuraSchool of Health Science, Sapporo Medical University, Sapporo 060-8556, Japan.
Hallie BuckleyDepartment of Anatomy, University of Otago, Dunedin 9054, New Zealand.
Kate DomettDivision of Tropical Health and Medicine, College of Medicine and Dentistry, James Cook University, Townsville, Queensland 4811, Australia.ORCID 0000-0001-5091-3105
Giang Hai NguyenDepartment of Prehistoric Archaeology, Vietnam Institute of Archaeology, Hanoi, Vietnam.
Hoang Hiep TrinhDepartment of Prehistoric Archaeology, Vietnam Institute of Archaeology, Hanoi, Vietnam.
Aung Aung KyawDepartment of Archaeology, Ministry of Religious Affairs and Culture, Mandalay, Myanmar.ORCID 0000-0001-7711-4100
Tin Tin WinDepartment of Archaeology, Ministry of Religious Affairs and Culture, Mandalay, Myanmar.
Baptiste PradierUMR 7055 Préhistoire et Technologie, Université Paris Nanterre, 92023 Nanterre, France.ORCID 0000-0002-0169-7589
Nasreen BroomandkhoshbachtDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Francesca CandilioSoprintendenza Archeologia Belle Arti e Paesaggio per la Città Metropolitana di Cagliari e per le Province di Oristano e Sud Sardegna, 09124 Cagliari, Italy.ORCID 0000-0002-4668-1361
Piya ChangmaiDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, 70103 Ostrava, Czech Republic.ORCID 0000-0003-3307-0585
Daniel FernandesDepartment of Anthropology, University of Vienna, 1090 Vienna, Austria.
Matthew FerryDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0001-7319-0085
Beatriz GamarraEarth Institute, University College Dublin, Dublin 4, Ireland.
Eadaoin HarneyDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Jatupol KampuansaiDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Wibhu KutananDepartment of Biology, Faculty of Science, Khon Kaen University, Khon Kaen, 40002, Thailand.ORCID 0000-0001-7767-1644
Megan MichelDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Mario NovakEarth Institute, University College Dublin, Dublin 4, Ireland.
Jonas OppenheimerDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0001-7973-6173
Kendra SirakEarth Institute, University College Dublin, Dublin 4, Ireland.
Kristin StewardsonDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Zhao ZhangDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-7562-7559
Pavel FlegontovDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, 70103 Ostrava, Czech Republic.
Ron PinhasiDepartment of Anthropology, University of Vienna, 1090 Vienna, Austria. mlipson@genetics.med.harvard.edu ron.pinhasi@univie.ac.at reich@genetics.med.harvard.edu.ORCID 0000-0003-1629-8131
David ReichDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA. mlipson@genetics.med.harvard.edu ron.pinhasi@univie.ac.at reich@genetics.med.harvard.edu.
Howard Hughes Medical Institute · USUniversity College Dublin · IEHarvard University · USBroad Institute · USMandalay University · MMUniversity of Ostrava · CZVietnam Academy of Social Sciences · VNAustralian Institute of Tropical Health and Medicine · AUAustralian National University · AUCentre National de la Recherche Scientifique · FRChiang Mai University · THJames Cook University · AUKhon Kaen University · THSapporo Medical University · JPUniversité Paris Nanterre · FRUniversity of Hawaiʻi at Mānoa · USUniversity of Otago · NZUniversity of Pennsylvania · US

Funding

Population mixture in evolutionary and medical geneticsR01GM100233 · NIGMS · HARVARD MEDICAL SCHOOL · PI PATTERSON, NICK J, REICH, DAVID E · 2012 to 2019
$2.7M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM100233
6 · The paper itself

Abstract

Southeast Asia is home to rich human genetic and linguistic diversity, but the details of past population movements in the region are not well known. Here, we report genome-wide ancient DNA data from 18 Southeast Asian individuals spanning from the Neolithic period through the Iron Age (4100 to 1700 years ago). Early farmers from Man Bac in Vietnam exhibit a mixture of East Asian (southern Chinese agriculturalist) and deeply diverged eastern Eurasian (hunter-gatherer) ancestry characteristic of Austroasiatic speakers, with similar ancestry as far south as Indonesia providing evidence for an expansive initial spread of Austroasiatic languages. By the Bronze Age, in a parallel pattern to Europe, sites in Vietnam and Myanmar show close connections to present-day majority groups, reflecting substantial additional influxes of migrants.

Indexed as

Genome, HumanAgricultureAsian PeopleAsia, SoutheasternDNA, AncientGenetic VariationHistory, AncientHuman MigrationHumansLanguageRadiometric DatingDNA, Ancient

Identifiers

PMID29773666
PMCPMC6476732
OpenAlexW2794079675

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.