Evidence map›Paper›PMID 29773658›Full record

ArticleGenome research2018

Detecting, quantifying, and discriminating the mechanism of mosaic chromosomal aneuploidies using MAD-seq.

Yu Kong, Esther R Berko, Anthony Marcketta, Shahina B Maqbool, Claudia A Simões-Pires, David F Kronn, Kenny Q Ye, Masako Suzuki, Adam Auton, John M Greally

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genome research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yu Kong *Department of Genetics and Center for Epigenomics, Albert Einstein College of Medicine, New York, New York 10461, USA.
Esther R Berko *Department of Genetics and Center for Epigenomics, Albert Einstein College of Medicine, New York, New York 10461, USA.
Anthony MarckettaDepartment of Genetics and Center for Epigenomics, Albert Einstein College of Medicine, New York, New York 10461, USA.
Shahina B MaqboolDepartment of Genetics and Center for Epigenomics, Albert Einstein College of Medicine, New York, New York 10461, USA.
Claudia A Simões-PiresDepartment of Genetics and Center for Epigenomics, Albert Einstein College of Medicine, New York, New York 10461, USA.
David F KronnDepartment of Pediatrics, New York Medical College, Valhalla, New York 10595, USA.
Kenny Q YeDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, New York 10461, USA.
Masako SuzukiDepartment of Genetics and Center for Epigenomics, Albert Einstein College of Medicine, New York, New York 10461, USA.
Adam AutonDepartment of Genetics and Center for Epigenomics, Albert Einstein College of Medicine, New York, New York 10461, USA.
John M GreallyDepartment of Genetics and Center for Epigenomics, Albert Einstein College of Medicine, New York, New York 10461, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current approaches to detect and characterize mosaic chromosomal aneuploidy are limited by sensitivity, efficiency, cost, or the need to culture cells. We describe the mosaic aneuploidy detection by massively parallel sequencing (MAD-seq) capture assay and the

Indexed as

AneuploidyChromosomesExomeFemaleGenomeHigh-Throughput Nucleotide SequencingHumansMaleMosaicismSoftware

Identifiers

PMID29773658
PMCPMC6028128

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.