Trial reportAmerican journal of preventive medicine2018
Addressing Parents' Vaccine Concerns: A Randomized Trial of a Social Media Intervention.
Trial report in American journal of preventive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01873040 (Randomized Intervention Trial to Evaluate a Vaccine Social Media Website), which is not on this map. Cited by 92 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Intervention Trial to Evaluate a Vaccine Social Media Website
Who cites it
92 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Media Exposure and Its Association With Vaccine Attitudes, Intentions, and Hesitancy: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Social media-based interventions for improving vaccine uptake, reducing hesitancy, and combating misinformation: a comprehensive systematic review and meta-analysis of RCT.BMC public health · 2026Pooled it
- Interventions Addressing Vaccine Hesitancy in the WHO European Region and in North America (United States and Canada): A Systematic Review.Public health reviews · 2026Pooled it
- Tailoring educational interventions targeting parental vaccine hesitancy: a systematic review of quantitative studies.Frontiers in public health · 2026Pooled it
- Social Media as an Effective Provider of Quality-Assured and Accurate Information to Increase Vaccine Rates: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Behavioral interventions for vaccination uptake: A systematic review and meta-analysis.Health policy (Amsterdam, Netherlands) · 2023Pooled it
- Vaccine hesitancy and behavior change theory-based social media interventions: a systematic review.Translational behavioral medicine · 2022Pooled it
- Behavioural interventions delivered through interactive social media for health behaviour change, health outcomes, and health equity in the adult population.The Cochrane database of systematic reviews · 2021Pooled it
- Factors affecting the vaccination choices of pregnant women for their children: a systematic review of the literature.Human vaccines & immunotherapeutics · 2020Pooled it
- Human-centred design bolsters vaccine confidence in the Philippines: results of a randomised controlled trial.BMJ global health · 2023Trial
- Scaling and sustaining COVID-19 vaccination through meaningful community engagement and care coordination for underserved communities: hybrid type 3 effectiveness-implementation sequential multiple assignment randomized trial.Implementation science : IS · 2023Trial
- A randomized controlled trial of a video intervention shows evidence of increasing COVID-19 vaccination intention.PloS one · 2022Trial
- Social Media Vaccine Websites: A Comparative Analysis of Public and Moderated Websites.Health education & behavior : the official publication of the Society for Public Health Education · 2019Trial
- Parental acceptability of new RSV preventive therapies for infants: A cross-sectional survey in Canada.Human vaccines & immunotherapeutics · 2026Article
- Impact of social media use on influenza vaccine hesitancy among pediatric healthcare workers: The mediating role of 3Cs.Human vaccines & immunotherapeutics · 2026Article
- A Community Grounded Approach to Addressing COVID-19 Health Disparities and Misinformation in Latinx and Indigenous Mexican Immigrant Communities.Journal of community health · 2026Article
- Associating Race, Income, and Discrimination with COVID-19 Vaccine Status, Hesitancy, and Access in the United States: A Cross-sectional Study.Journal of racial and ethnic health disparities · 2026Article
- The effects of health fatalism and cyberchondria on parents' childhood vaccine hesitancy.BMC public health · 2026Article
- Illustrating Key Components to Co-Creation Through Preventive Care mHealth Messaging with Underserved Communities and Expert Partners.Journal of medical systems · 2025Article
- The Determinants of Influenza Vaccine Uptake in Pregnant Women During the COVID-19 Pandemic Using the Theory of Planned Behavior: A Cross-Sectional Study.Maternal and child health journal · 2025Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
introductionSuccessful strategies are needed to address parental vaccine hesitancy, a significant public health issue. The study objective was to assess whether an Internet-based platform with vaccine information and interactive social media components improved parents' vaccine-related attitudes. STUDY
designA three-arm RCT. SETTING/
participantsThe study was conducted in a large Colorado integrated healthcare organization. Parents were enrolled during September 2013 through October 2015 and followed through November 2016; data were analyzed in 2017. Parents, recruited during pregnancy, were given a survey about vaccine-related attitudes at enrollment (i.e., baseline) and when their child was aged 3-5 months and 12-15 months (Timepoints 1 and 2, respectively). Parental vaccine hesitancy was assessed at baseline.
interventionStudy participants were randomized to the following: a study website with vaccine information and social media components (VSM arm); a website with vaccine information only (VI); or usual care.
main outcome measuresChange in parental vaccine attitudes over time by baseline degree of vaccine hesitancy.
resultsAmong 1,093 study participants, 945 (86.5%) completed all three surveys. Comparing baseline with Timepoint 1 among vaccine-hesitant parents, the VSM and VI arms were associated with significant improvements in attitudes regarding vaccination benefits compared to usual care (VSM mean change 0.23 on a 5-point scale, 95% CI=0.05, 0.40, VI mean change 0.22, 95% CI=0.04, 0.40). Comparing baseline with Timepoint 2 among hesitant parents, the VSM and VI arms were also associated with significant reductions in parental concerns about vaccination risks compared to usual care (VSM mean change -0.37, 95% CI= -0.60, -0.14, VI mean change -0.31, 95% CI= -0.55, -0.07). Self-efficacy around vaccine decision making also improved among vaccine-hesitant parents. No intervention effect was observed among parents not vaccine-hesitant at baseline.
conclusionsAmong vaccine-hesitant parents, an Internet-based intervention improved parents' attitudes about vaccines.
trial registrationThis study was registered at www.clinicaltrials.gov NCT01873040.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.