Evidence map›Paper›PMID 29773309›Full record

ArticleGeneral hospital psychiatry

Posttraumatic stress disorder in patients who rule out versus rule in for acute coronary syndrome.

Ian M Kronish, Donald Edmondson, Nathalie Moise, Bernard P Chang, Ying Wei, David Lopez Veneros, William Whang

Abstract read
In one paragraph

Article in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. Review
  6. Article
  7. Intervening on fear after acute cardiac events: Rationale and design of the INFORM randomized clinical trial.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2020
    Article
  8. Article
  9. Article
  10. Observational
  11. Stressing Out About the Heart: A Narrative Review of the Role of Psychological Stress in Acute Cardiovascular Events.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2020
    Review
  12. Article
  13. Development and Validation of a Measure to Assess Patients' Threat Perceptions in the Emergency Department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2018
    Observational
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ian M KronishCenter for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 W. 168th St, New York, NY 10032, USA. Electronic address: ik2293@cumc.columbia.edu.
Donald EdmondsonCenter for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 W. 168th St, New York, NY 10032, USA.
Nathalie MoiseCenter for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 W. 168th St, New York, NY 10032, USA.
Bernard P ChangDepartment of Emergency Medicine, Columbia University Medical Center, 622 W. 168th St, New York, NY 10032, USA.
Ying WeiDepartment of Biostatistics, Mailman School of Public Health, Columbia University, 722 West 168th St, New York, NY, 10032, USA.
David Lopez VenerosCenter for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 W. 168th St, New York, NY 10032, USA.
William WhangCenter for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 W. 168th St, New York, NY 10032, USA.
Columbia University Irving Medical Center · USColumbia University · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Testing biopsychosocial mechanisms of the posthospital syndrome model ofearly rehospitalization in acute coronary syndrome patientsR01HL128497 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EDMONDSON, DONALD · 2016 to 2019
$3.7M
Impact of Social-Interpersonal Factors in the ER on PTSD/Cardiac OutcomesR01HL117832 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W., EDMONDSON, DONALD · 2013 to 2017
$3.1M
Test of a new theory to explain excess risk in cardiac PTSDR01HL128310 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EDMONDSON, DONALD · 2015 to 2018
$2.6M
PTSD, Medication Adherence, and Prognosis after Acute Coronary SyndromesR01HL123368 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W., KRONISH, IAN MATTHEW · 2014 to 2017
$1.6M
NCATS NIH HHS UL1 TR001873NHLBI NIH HHS R01 HL117832NHLBI NIH HHS R01 HL123368NHLBI NIH HHS R01 HL128310NHLBI NIH HHS R01 HL128497
6 · The paper itself

Abstract

objectiveMany patients who present to the emergency department (ED) with acute coronary syndromes (ACS) develop posttraumatic stress disorder (PTSD) due to the experience. Less is known about risk for PTSD in patients who rule out for ACS. Our objective was to compare the risk of developing PTSD among patients who rule out versus rule in for ACS.

methodsWe enrolled a consecutive sample of 1000 patients presenting to an emergency department (ED) with symptoms of a probable ACS. We assessed presenting ACS symptoms in the ED. We determined whether presenting symptoms were due to a confirmed ACS or another etiology by chart review. We assessed PTSD by telephone 1 month after discharge using the PTSD Checklist specific for the suspected ACS event (PCL-S). We used logistic regression to determine the association of ruling out versus ruling in for ACS with a positive PTSD screen (PCL-S ≥ 32), adjusting for demographics, comorbidities, depression, trauma history, and pre-existing PTSD.

resultsApproximately two-thirds of patients (68.2%) ruled out for ACS. Compared to confirmed ACS patients, patients who ruled out had similar presenting symptoms, and similar risk of screening positive for PTSD (18.9% versus 16.8%; p = 0.47; adjusted OR 1.18, 95% CI 0.69-2.00; p = 0.55).

conclusionsED presentation with ACS symptoms was sufficient to trigger a positive PTSD screen whether the etiology was due to a life-threatening ACS or another etiology. Patients who present with ACS symptoms should be considered for interventions to prevent PTSD after hospitalization, regardless of symptom etiology.

Indexed as

Acute Coronary SyndromeAdultAgedChest PainEmergency Service, HospitalFemaleFollow-Up StudiesHumansMaleMiddle AgedStress Disorders, Post-TraumaticAcute coronary syndromeCardiovascular diseaseEmergency departmentEtiologyPosttraumatic stress disorderTrauma

Identifiers

PMID29773309
PMCPMC6291417
OpenAlexW2804255327

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.