Evidence map›Paper›PMID 29772796›Full record

ArticleMarine drugs2018

Precursor-Directed Generation of Indolocarbazoles with Topoisomerase IIα Inhibitory Activity.

Cong Wang, Adeep Monger, Liping Wang, Peng Fu, Pawinee Piyachaturawat, Arthit Chairoungdua, Weiming Zhu

Abstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. MarineMarine drugs · 2024
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cong WangKey Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China. wangcong123206@163.com.
Adeep MongerToxicology Graduate Program, Department of Physiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand. adeepmonger11@gmail.com.ORCID 0000-0002-3912-6351
Liping WangKey Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550002, China. lipingw2006@163.com.
Peng FuKey Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China. fupeng@ouc.edu.cn.
Pawinee PiyachaturawatToxicology Graduate Program, Department of Physiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand. pawinee.pia@mahidol.ac.th.
Arthit ChairoungduaToxicology Graduate Program, Excellent Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok 10400, Thailand. arthit.chi@mahidol.ac.th.
Weiming ZhuKey Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China. weimingzhu@ouc.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One new indolocarbazole, 3-hydroxy-K252d (

Indexed as

5-HydroxytryptophanApoptosisApoptosis Regulatory ProteinsAquatic OrganismsCarbazolesCell Line, TumorDNA Topoisomerases, Type IIDrug Screening Assays, AntitumorEnzyme AssaysHumansInhibitory Concentration 50StreptomycesTopoisomerase II Inhibitors3-hydroxy-K252d5-HydroxytryptophanApoptosis Regulatory ProteinsCarbazolesDNA Topoisomerases, Type IITopoisomerase II Inhibitorscytotoxicitiesindolocarbazolemarine-derived StreptomycesStreptomyces sp. OUCMDZ-3118topoisomerase IIα enzyme activity

Identifiers

PMID29772796
PMCPMC5983299

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.