Evidence map›Paper›PMID 29772692›Full record

ArticleJournal of personalized medicine2018

Insurance Coverage Policies for Pharmacogenomic and Multi-Gene Testing for Cancer.

Christine Y Lu, Stephanie Loomer, Rachel Ceccarelli, Kathleen M Mazor, James Sabin, Ellen Wright Clayton, Geoffrey S Ginsburg, Ann Chen Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Detection accuracy and clinical applications of DP-TOF mass spectrometry.The Journal of international medical research · 2024
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  19. Development and implementation of an electronic medical record module to track genetic testing results.Genetics in medicine : official journal of the American College of Medical Genetics · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christine Y LuPrecision Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Drive, Suite 401 East, Boston, MA 02215, USA. christine_lu@harvardpilgrim.org.
Stephanie LoomerPrecision Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Drive, Suite 401 East, Boston, MA 02215, USA. stephanie_loomer@harvardpilgrim.org.
Rachel CeccarelliPrecision Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Drive, Suite 401 East, Boston, MA 02215, USA. ceccare1@msu.edu.
Kathleen M MazorMeyers Primary Care Institute, A Joint Endeavor of the University of Massachusetts Medical School, Reliant Medical Group and Fallon Health; 630 Plantation Street, Worcester, MA 01605, USA. Kathy.Mazor@meyersprimary.org.
James SabinDepartments of Population Medicine and Psychiatry, Harvard Medical School, Boston, MA 02115, USA. jim_sabin@harvardpilgrim.org.
Ellen Wright ClaytonCenter for Biomedical Ethics and Society, Vanderbilt University Medical Center, Nashville, TN 37232, USA. ellen.clayton@vanderbilt.edu.ORCID 0000-0002-0308-4110
Geoffrey S GinsburgDuke Center for Applied Genomics and Precision Medicine, Duke University Medical Center, Durham, NC 27710, USA. geoffrey.ginsburg@duke.edu.
Ann Chen WuPrecision Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Drive, Suite 401 East, Boston, MA 02215, USA. ann.wu@childrens.harvard.edu.

Funding

Genomics-based Technologies: Access and Reimbursement IssuesR21HG008510 · NHGRI · HARVARD PILGRIM HEALTH CARE, INC. · PI LU, CHRISTINE, WU, ANN CHEN · 2015 to 2016
$539k
NHGRI NIH HHS R21 HG008510
6 · The paper itself

Abstract

Insurance coverage policies are a major determinant of patient access to genomic tests. The objective of this study was to examine differences in coverage policies for guideline-recommended pharmacogenomic tests that inform cancer treatment. We analyzed coverage policies from eight Medicare contractors and 10 private payers for 23 biomarkers (e.g.,

Indexed as

cancerinsurance coveragemulti-gene testingpharmacogenomicstumor markers

Identifiers

PMID29772692
PMCPMC6023380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.