Evidence map›Paper›PMID 29772530›Full record

ReviewFrontiers in bioscience (Landmark edition)2018

Deciphering mechanism of conformationally controlled electron transfer in nitric oxide synthases.

Jinghui Li, Huayu Zheng, Changjian Feng

Open access · greenAbstract readReview
In one paragraph

Review in Frontiers in bioscience (Landmark edition), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Analyzing the FMN-heme interdomain docking interactions in neuronal and inducible NOS isoforms by pulsed EPR experiments and conformational distribution modeling.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
  3. Probing calmodulin-NO synthase interactions via site-specific infrared spectroscopy: an introductory investigation.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. An isoform-specific pivot modulates the electron transfer between the flavin mononucleotide and heme centers in inducible nitric oxide synthase.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2020
    Article
  8. Review
  9. Article
  10. Generation and characterization of functional phosphoserine-incorporated neuronal nitric oxide synthase holoenzyme.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jinghui LiCollege of Pharmacy, University of New Mexico, Albuquerque, NM 87131, USA.
Huayu ZhengCollege of Pharmacy, University of New Mexico, Albuquerque, NM 87131, USA.
Changjian FengUniversity of New Mexico, MSC 09 5360, Albuquerque, NM 87131, cfeng@unm.edu.
University of New Mexico · US

Funding

Mechanisms of Electron Transfer in Nitric Oxide Synthases: the Output State in NiR15GM081811 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI FENG, CHANGJIAN · 2007 to 2016
$1.0M
Novel Receptor-Targeting Theranostic Peptides for Prostate CancerR15CA173516 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI FENG, CHANGJIAN · 2013 to 2013
$453k
NCI NIH HHS R15 CA173516NIGMS NIH HHS R15 GM081811
6 · The paper itself

Abstract

Electron transfer is a fundamental process in life that is very often coupled to catalysis within redox enzymes through a stringent control of protein conformational movements. Mammalian nitric oxide synthase (NOS) proteins are redox flavo-hemoproteins consisting of multiple modular domains. The NOS enzyme is exquisitely regulated

Indexed as

AnimalsBiocatalysisCalciumCalmodulinElectron TransportHumansIsoenzymesNitric OxideNitric Oxide SynthaseProtein ConformationCalciumCalmodulinIsoenzymesNitric OxideNitric Oxide Synthase

Identifiers

PMID29772530
PMCPMC11167721
OpenAlexW2803911266

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.