Evidence map›Paper›PMID 29771941›Full record

ArticlePLoS neglected tropical diseases2018

Efficacy of ivermectin mass-drug administration to control scabies in asylum seekers in the Netherlands: A retrospective cohort study between January 2014 - March 2016.

Dorien T Beeres, Sofanne J Ravensbergen, Annelies Heidema, Darren Cornish, Machiel Vonk, Leonie D Wijnholds, Jessica J H Hendriks, Johanneke Kleinnijenhuis, Till F Omansen, Ymkje Stienstra

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Phytomedicines and conventional drugs in scabies management.GMS hygiene and infection control · 2026
    Review
  3. Article
  4. Article
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  7. Article
  8. Review
  9. Article
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  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Increase of scabies infestations, Norway, 2006 to 2018.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
  17. Article
  18. Article
  19. Control Strategies for Scabies.Tropical medicine and infectious disease · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Dorien T BeeresUniversity of Groningen, Department of Internal Medicine, Infectious Disease Unit, University Medical Centre Groningen, Groningen, The Netherlands.
Sofanne J RavensbergenUniversity of Groningen, Department of Internal Medicine, Infectious Disease Unit, University Medical Centre Groningen, Groningen, The Netherlands.ORCID 0000-0002-5964-8405
Annelies HeidemaPrimary Health Care Centre for Asylum Seekers (GCA), Ter Apel, The Netherlands.
Darren CornishBabylon Primary Health Care Services, Elst, The Netherlands.
Machiel VonkMunicipal health Care Centre Groningen, Groningen, The Netherlands.
Leonie D WijnholdsMediq pharmacy Ter Apel, Ter Apel, The Netherlands.
Jessica J H HendriksHealth Care Service for Asylum seekers (Gezondheidscentrum Asielzoekers), Wageningen, The Netherlands.
Johanneke KleinnijenhuisUniversity of Groningen, Department of Internal Medicine, Infectious Disease Unit, University Medical Centre Groningen, Groningen, The Netherlands.
Till F OmansenUniversity of Groningen, Department of Internal Medicine, Infectious Disease Unit, University Medical Centre Groningen, Groningen, The Netherlands.
Ymkje StienstraUniversity of Groningen, Department of Internal Medicine, Infectious Disease Unit, University Medical Centre Groningen, Groningen, The Netherlands.
University Medical Center Groningen · NLDialyse Centrum Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scabies is a skin infestation with the mite Sarcoptes scabiei causing itch and rash and is a major risk factor for bacterial skin infections and severe complications. Here, we evaluated the treatment outcome of 2866 asylum seekers who received (preventive) scabies treatment before and during a scabies intervention programme (SIP) in the main reception centre in the Netherlands between January 2014 and March 2016. A SIP was introduced in the main national reception centre based on frequent observations of scabies and its complications amongst Eritrean and Ethiopian asylum seekers in the Netherlands. On arrival, all asylum seekers from Eritrea or Ethiopia were checked for clinical scabies signs and received ivermectin/permethrin either as prevention or treatment. A retrospective cohort study was conducted to compare the reinfestations and complications of scabies in asylum seekers who entered the Netherlands before and during the intervention and who received ivermectin/permethrin. In total, 2866 asylum seekers received treatment during the study period (January 2014 -March 2016) of which 1359 (47.4%) had clinical signs of scabies. During the programme, most of the asylum seekers with scabies were already diagnosed on arrival as part of the SIP screening (580 (64.7%) of the 897). Asylum seekers with more than one scabies episode reduced from 42.0% (194/462) before the programme to 27.2% (243/897) during the programme (RR = 0.64, 95% CI = 0.55-0.75). Development of scabies complications later in the asylum procedure reduced from 12.3% (57/462) to 4.6% (41/897). A scabies prevention and treatment programme at start of the asylum procedure was feasible and effective in the Netherlands; patients were diagnosed early and risk of reinfestations and complications reduced. To achieve a further decrease of scabies, implementation of the programme in multiple asylum centres may be needed.

Indexed as

AcaricidesAdolescentAdultAnimalsFemaleHumansIvermectinMaleMiddle AgedNetherlandsRefugeesRetrospective StudiesSarcoptes scabieiScabiesYoung AdultAcaricidesIvermectin

Identifiers

PMID29771941
PMCPMC5957329
OpenAlexW2804708887

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.