ArticlePLoS genetics2018
Elevated temperature increases meiotic crossover frequency via the interfering (Type I) pathway in Arabidopsis thaliana.
Article in PLoS genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 85 citations in OpenAlex.
- SNI1/NSE5 is a cold-sensitive brake on class II crossovers in Arabidopsis.Nature plants · 2026Article
- The meiotic achilles' heel: vulnerability and resilience under environmental stress.Protoplasma · 2026Review
- Crossover control: A key to unlocking genetic diversity in plant breeding.Journal of integrative plant biology · 2026Review
- Breeding better crops: lessons from the homologous recombination pathway.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Review
- Epitranscriptomic RNA editing resolves Mus81 DNA repair tradeoffs in heat tolerance and meiosis.Nature communications · 2026Article
- Conserved differential expression of DDX helicase and CPEB genes in skeletal muscles potentially influences neuromuscular junctions during aging: a computational analysis.Biogerontology · 2026Article
- Article
- mop1 affects maize recombination landscapes by modulating methylation of MITEs near genes in open chromatin.Nature communications · 2025Article
- Impacts of temperature on recombination rate and meiotic success in thermotolerant and cold-tolerant yeast species.Heredity · 2025Article
- Molecular aspects of heat stress sensing in land plants.The Plant journal : for cell and molecular biology · 2025Review
- Temperature regulates negative supercoils to modulate meiotic crossovers and chromosome organization.Science China. Life sciences · 2024Article
- Article
- Control of meiotic crossover interference by a proteolytic chaperone network.Nature plants · 2024Article
- Impact of feralization on evolutionary trajectories in the genomes of feral cat island populations.PloS one · 2024Article
- Epigenetic regulation during meiosis and crossover.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Review
- Technology-driven approaches for meiosis research in tomato and wild relatives.Plant reproduction · 2023Article
- Creating novel ornamentalsFrontiers in plant science · 2023Review
- The impact of heat stress in plant reproduction.Frontiers in plant science · 2023Review
- Heat shock protein 101 contributes to the thermotolerance of male meiosis in maize.The Plant cell · 2022Article
- Arabidopsis HEAT SHOCK FACTOR BINDING PROTEIN is required to limit meiotic crossovers and HEI10 transcription.The EMBO journal · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For most eukaryotes, sexual reproduction is a fundamental process that requires meiosis. In turn, meiosis typically depends on a reciprocal exchange of DNA between each pair of homologous chromosomes, known as a crossover (CO), to ensure proper chromosome segregation. The frequency and distribution of COs are regulated by intrinsic and extrinsic environmental factors, but much more is known about the molecular mechanisms governing the former compared to the latter. Here we show that elevated temperature induces meiotic hyper-recombination in Arabidopsis thaliana and we use genetic analysis with mutants in different recombination pathways to demonstrate that the extra COs are derived from the major Type I interference sensitive pathway. We also show that heat-induced COs are not the result of an increase in DNA double-strand breaks and that the hyper-recombinant phenotype is likely specific to thermal stress rather than a more generalized stress response. Taken together, these findings provide initial mechanistic insight into how environmental cues modulate plant meiotic recombination and may also offer practical applications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.