Evidence map›Paper›PMID 29771492›Full record

ArticleACS chemical neuroscience2018

Hyperpolarized

Yuhei Takado, Tian Cheng, Jessica A M Bastiaansen, Hikari A I Yoshihara, Bernard Lanz, Mor Mishkovsky, Sylvain Lengacher, Arnaud Comment

Open access · greenAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Tracking Hyperpolarized [1-NMR in biomedicine · 2025
    Article
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. In VivoNeurochemical research · 2022
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Probing Cerebral Metabolism with HyperpolarizedACS chemical neuroscience · 2021
    Article
  17. Review
  18. Article
  19. Hyperpolarized [1-Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  20. Functional Genetic Screening Enables Theranostic Molecular Imaging in Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Yuhei TakadoInstitute of Physics of Biological Systems , Ecole Polytechnique Fédérale de Lausanne , CH-1015 Lausanne , Switzerland.
Tian ChengCancer Research UK Cambridge Institute , University of Cambridge , Li Ka Shing Centre , Cambridge , United Kingdom.
Jessica A M BastiaansenLaboratory of Functional and Metabolic Imaging , Ecole Polytechnique Fédérale de Lausanne , CH-1015 Lausanne , Switzerland.
Hikari A I YoshiharaInstitute of Physics of Biological Systems , Ecole Polytechnique Fédérale de Lausanne , CH-1015 Lausanne , Switzerland.
Bernard LanzSir Peter Mansfield Magnetic Resonance Center , The University of Nottingham , Nottingham NG7 2RD , United Kingdom.
Mor MishkovskyLaboratory of Functional and Metabolic Imaging , Ecole Polytechnique Fédérale de Lausanne , CH-1015 Lausanne , Switzerland.
Sylvain LengacherLaboratory of Neuroenergetics and Cellular Dynamics , Ecole Polytechnique Fédérale de Lausanne , CH-1015 Lausanne , Switzerland.
Arnaud CommentInstitute of Physics of Biological Systems , Ecole Polytechnique Fédérale de Lausanne , CH-1015 Lausanne , Switzerland.ORCID 0000-0002-8484-3448
École Polytechnique Fédérale de Lausanne · CHBuckinghamshire Healthcare NHS Trust · GBNational Institutes for Quantum Science and Technology · JPUniversity of Cambridge · GBUniversity of Nottingham · GB

Funding

European Research Council 682574
6 · The paper itself

Abstract

The dynamics of l-lactate transport across the blood-brain barrier (BBB) and its cerebral metabolism are still subject to debate. We studied lactate uptake and intracellular metabolism in the mouse brain using hyperpolarized

Indexed as

AnimalsBlood-Brain BarrierBrainCarbon-13 Magnetic Resonance SpectroscopyLactic AcidL-Lactate DehydrogenaseMaleMiceMice, Inbred C57BLPyruvic AcidUltrasonic WavesLactic AcidL-Lactate DehydrogenasePyruvic Acidbicarbonatedynamic nuclear polarizationHyperpolarizationmagnetic resonance spectroscopypyruvateultrasound

Identifiers

PMID29771492
PMCPMC6119468
OpenAlexW2803309798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.