Evidence map›Paper›PMID 29771178›Full record

ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2019

Islet Microvasculature Alterations With Loss of Beta-cells in Patients With Type 1 Diabetes.

Joseph S Canzano, Lith H Nasif, Elizabeth A Butterworth, Dongtao A Fu, Mark A Atkinson, Martha Campbell-Thompson

Open access · bronzeAbstract read
In one paragraph

Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Diabetes as a Pancreatic Microvascular Disease-A Pericytic Perspective.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2024
    Review
  8. Understanding the Structural Arrangement of Islets in Chronic Pancreatitis.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss.American journal of physiology. Endocrinology and metabolism · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Joseph S CanzanoDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida.
Lith H NasifDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida.
Elizabeth A ButterworthDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida.
Dongtao A FuDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida.
Mark A AtkinsonDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida.ORCID 0000-0001-8489-4782
Martha Campbell-ThompsonDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida.ORCID 0000-0001-6878-1235
University of Florida · US

Funding

Neuromodulation-based treatment of diabetes: identifying anatomical and physiological pancreatic innervation targetsOT2OD023861 · OD · UNIVERSITY OF FLORIDA · PI CAMPBELL-THOMPSON, MARTHA · 2016 to 2018
$1.7M
Defining Islet Heterogeneity Using Single Islet TranscriptomicsUC4DK104155 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI CAMPBELL-THOMPSON, MARTHA, GERLING, IVAN C · 2014 to 2014
$1.6M
NIDDK NIH HHS UC4 DK104155NIH HHS OT2 OD023861
6 · The paper itself

Abstract

Islet microvasculature provides key architectural and functional roles, yet the morphological features of islets from patients with type 1 diabetes are poorly defined. We examined islet and exocrine microvasculature networks by multiplex immunofluorescence imaging of pancreases from organ donors with and without type 1 diabetes (

Indexed as

ActinsAdolescentAdultChildDiabetes Mellitus, Type 1FemaleFluorescent Antibody TechniqueHumansInsulinInsulin-Secreting CellsIslets of LangerhansMaleMicroscopy, ConfocalMicrovesselsTissue DonorsYoung AdultACTA2 protein, humanActinsInsulinalpha-cellCD3CD31CD34endotheliumexocrineglucagoninsulinmicroenvironmentsecretogranin 3smooth muscle actin

Identifiers

PMID29771178
PMCPMC6309032
OpenAlexW2804214868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.