ArticleClinical rheumatology2018
Body adiposity index, lipid accumulation product, and cardiometabolic index reveal the contribution of adiposity phenotypes in the risk of hyperuricemia among Chinese rural population.
Article in Clinical rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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43 citing papers in PubMed, 57 citations in OpenAlex.
- Linking the cardiometabolic index to coronary heart disease in groups with Diabetes and Prediabetes.Scientific reports · 2026Article
- Cardiometabolic index as a predictor of sarcopenia in U.S. adults aged 20-59: results from a cross-sectional study.Clinics (Sao Paulo, Brazil) · 2026Article
- Cardiometabolic index is associated with hypertension among US older adults: An analysis of NHANES 2011-2018.Medicine · 2026Article
- Association between cardiometabolic index and stage progression in cardiovascular-kidney-metabolic syndrome: insights from a Chinese population-based cohort study.European journal of medical research · 2026Article
- Association between Lipid Accumulation Product and 3-Month Functional Outcome after Ischemic Stroke: the Obesity-Stroke Paradox.Translational stroke research · 2026Article
- When Obesity Hits the Kidneys: Sex-Specific Effects of Visceral Adiposity Indices on Diabetic Kidney Disease Risk.Journal of nutrition and metabolism · 2026Article
- Higher cardiometabolic index elevates the risk of hyperuricemia in the elderly: findings from the China health and retirement longitudinal study.Annals of medicine · 2025Article
- Obesity paradox: association between lipid metabolism indices and skeletal muscle mass in older adults: the mediating role of uric acid.Acta diabetologica · 2025Article
- Association between cardiometabolic index and cardiometabolic multimorbidity in non-alcoholic fatty liver disease patients: evidence from a cross-sectional study.Scientific reports · 2025Article
- Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation.European journal of clinical investigation · 2025Review
- Effect of dietary approaches to stop hypertension diet on insulin resistance and lipid accumulation product in subjects with metabolic syndrome.Scientific reports · 2025Article
- Longitudinal changes and patterns in cardiometabolic index and the natural course of prediabetes in the China health and retirement longitudinal study.Lipids in health and disease · 2025Article
- Association between cardiometabolic index and hypertension among US adults from NHANES 1999-2020.Scientific reports · 2025Article
- Cardiometabolic index as a predictor of gallstone incidence in U.S. adults: insights from NHANES 2017-2020.BMC gastroenterology · 2025Article
- Association between cardiometabolic index and risk of testosterone deficiency in adult men: a cross-sectional study.BMC public health · 2025Article
- The effects and predictive values of novel anthropometric parameters on uric acid levels and hyperuricemia in adults.Scientific reports · 2025Article
- Association between cardiometabolic index and albuminuria: Evidence from NHANES 2017-2020.PloS one · 2025Article
- Nonlinear association of cardiometabolic index with hyperuricemia: insights from the NHANES 1999-2018 study.Frontiers in endocrinology · 2025Article
- The association between the cardiometabolic index and hyperuricemia: 2011-2016 NHANES.Frontiers in endocrinology · 2025Article
- Association between periodontitis and cardiometabolic index (CMI): a study from NHANES 2009-2014.Scientific reports · 2024Article
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8 authors at 2 institutions in 2 countries.
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Abstract
Adiposity phenotypes, estimated by higher body adiposity index (BAI), lipid accumulation product (LAP), and cardiometabolic index (CMI), has conferred increased metabolic risk. The relative contribution of BAI, LAP, and CMI in hyperuricemia, however, is unknown. We hypothesized that these obesity indicators would refine identification of hyperuricemia. Information on serum uric acid (SUA), fasting lipid profiles, and body adiposity measures (BAI, LAP, and CMI) were recorded in a cross-sectional population-based sample of 11,102 participants (≥ 35 years old) from China. BAI, LAP, and CMI were strong independent predictors of SUA in both sexes after correction for potential confounders. In multivariable models, odds ratio (OR) for hyperuricemia for 1 SD increment in BAI, LAP, and CMI were 1.361 (95% CI, 1.224-1.513), 1.393 (95% CI, 1.273-1.525), and 1.332 (95% CI, 1.224-1.448) in females, respectively. For males, these adiposity indices corresponded to an increased hyperuricemia risk of 14, 47, and 33%, respectively. Additionally, compared to the bottom category, females with the top quartile of BAI, LAP, and CMI showed higher adjusted odds of having hyperuricemia, with ORs of 2.064, 7.500, and 4.944, respectively. ORs for hyperuricemia were statistically significant in the fourth quartile of BAI (1.622 [1.258-2.091]), LAP (5.549 [3.907-7.880]), and CMI (3.878 [2.830-5.313]) of male subgroup. Accumulation of ectopic adiposity in general (quantified by increased BAI), and of visceral adipose tissue in particular (reflected by elevated LAP and CMI), provided important insight regarding hyperuricemia risk and might potentially shed further light on our understanding of the metabolic sequelae of obesity.
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