ArticleJournal of biophotonics2018
Functional optical coherence tomography of neurovascular coupling interactions in the retina.
Article in Journal of biophotonics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 30 citations in OpenAlex.
- Impact of Aging and Light Stimulation Parameters on Retinal Hyperemia Responses in Functional Optical Coherence Tomography Angiography.Investigative ophthalmology & visual science · 2025Article
- Functional OCT reveals anisotropic changes of retinal flicker-evoked vasodilation.Optics letters · 2024Article
- OCT Imaging in Murine Models of Alzheimer's Disease in a Systematic Review: Findings, Methodology and Future Perspectives.Biomedicines · 2024Review
- Intrinsic signal optoretinography revealing AD-induced retinal photoreceptor hyperexcitability before a detectable morphological abnormality.Optics letters · 2023Article
- Assessment of macular microvascular changes in children following treatment of anisometropic myopic amblyopia using optical coherence tomography angiography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Observational
- Light conditions influence optic nerve OCT angiography parameter in healthy subjects with neutral pupils.Scientific reports · 2023Article
- Functional OCT angiography reveals early retinal neurovascular dysfunction in diabetes with capillary resolution.Biomedical optics express · 2023Article
- Volumetric data analysis enabled spatially resolved optoretinogram to measure the functional signals in the living retina.Journal of biophotonics · 2022Article
- Phase-Sensitive Measurements of Depth-Dependent Signal Transduction in the Inner Plexiform Layer.Frontiers in medicine · 2022Article
- Functional Optical Coherence Tomography for Intrinsic Signal Optoretinography: Recent Developments and Deployment Challenges.Frontiers in medicine · 2022Review
- OCT-Angiography Findings in Patients with Amblyopia: Comparison between Healthy Controls, Treatment-Responsive, and Treatment-Unresponsive Amblyopic Patients.Diagnostics (Basel, Switzerland) · 2021Article
- Concurrent OCT and OCT angiography of retinal neurovascular degeneration in the 5XFAD Alzheimer's disease mice.Neurophotonics · 2021Article
- In vivo optoretinography of phototransduction activation and energy metabolism in retinal photoreceptors.Journal of biophotonics · 2021Article
- Functional intrinsic optical signal imaging for objective optoretinography of human photoreceptors.Experimental biology and medicine (Maywood, N.J.) · 2021Article
- Vascular morphology and blood flow signatures for differential artery-vein analysis in optical coherence tomography of the retina.Biomedical optics express · 2021Article
- Full-field flicker evoked changes in parafoveal retinal blood flow.Scientific reports · 2020Article
- Functional optical coherence tomography enablesBiomedical optics express · 2020Article
- Fast intrinsic optical signal correlates with activation phase of phototransduction in retinal photoreceptors.Experimental biology and medicine (Maywood, N.J.) · 2020Review
- Measurement and visualization of stimulus-evoked tissue dynamics in mouse barrel cortex using phase-sensitive optical coherence tomography.Biomedical optics express · 2020Article
- Functional OCT angiography reveals early physiological dysfunction of hyaloid vasculature in developing mouse eye.Experimental biology and medicine (Maywood, N.J.) · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
Quantitative evaluation of retinal neurovascular coupling is essential for a better understanding of visual function and early detection of eye diseases. However, there is no established method to monitor coherent interactions between stimulus-evoked neural activity and hemodynamic responses at high resolution. Here, we report a multimodal functional optical coherence tomography (OCT) imaging methodology to enable concurrent intrinsic optical signal (IOS) imaging of stimulus-evoked neural activity and hemodynamic responses at capillary resolution. OCT angiography guided IOS analysis was used to separate neural-IOS and hemodynamic-IOS changes in the same retinal image sequence. Frequency flicker stimuli evoked neural-IOS changes in the outer retina; that is, photoreceptor layer, first and then in the inner retina, including outer plexus layer (OPL), inner plexiform layer (IPL), and ganglion cell layer (GCL), which were followed by hemodynamic-IOS changes primarily in the inner retina; that is, OPL, IPL, and GCL. Different time courses and signal magnitudes of hemodynamic-IOS responses were observed in blood vessels with various diameters.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.