Evidence map›Paper›PMID 29770434›Full record

ArticleImmunology2018

Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer.

Rong Yang, Ting-Ting Cai, Xiao-Jun Wu, Yi-Na Liu, Jia He, Xiao-Shi Zhang, Gang Ma, Jiang Li

Open access · bronzeAbstract read
In one paragraph

Article in Immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  8. Microbial manipulators:Journal of oral microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rong YangState Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, China.
Ting-Ting CaiState Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, China.
Xiao-Jun WuState Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, China.
Yi-Na LiuState Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, China.
Jia HeDepartment of Biotherapy, Sun Yat-Sen University Cancer Centre, Guangzhou, China.
Xiao-Shi ZhangState Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, China.
Gang MaIntensive Care Unit Department, Sun Yat-Sen University Cancer Centre, Guangzhou, China.
Jiang LiState Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, China.ORCID 0000-0001-5596-9159
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expansion of myeloid-derived suppressor cells (MDSCs) correlates with tumorigenesis in colorectal cancer (CRC). Here, we found a significant association between CD33

Indexed as

Biomarkers, TumorAdaptor Proteins, Signal TransducingAdultAgedAged, 80 and overBiomarkersCell ProliferationColorectal NeoplasmsFemaleGene Expression Regulation, NeoplasticGranulocyte-Macrophage Colony-Stimulating FactorHumansMaleMiddle AgedMyeloid-Derived Suppressor CellsNeoplasm GradingAdaptor Proteins, Signal TransducingBiomarkersBiomarkers, TumorGranulocyte-Macrophage Colony-Stimulating FactorPhosphoproteinsPTEN PhosphohydrolasePTEN protein, humanTranscription FactorsYAP1 protein, humanYAP-Signaling Proteinscolorectal cancermyeloid-derived suppressor cellphosphatase and tensin homologueprognosisyes-associated protein 1

Identifiers

PMID29770434
PMCPMC6142285
OpenAlexW2803446759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.