Evidence map›Paper›PMID 29770302›Full record

ArticleGland surgery2018

Percutaneous microwave thermosphere ablation of pancreatic tumours.

Anna Maria Ierardi, Pierpaolo Biondetti, Andrea Coppola, Enrico Maria Fumarola, Alberto Magenta Biasina, Salvatore Alessio Angileri, Gianpaolo Carrafiello

Open access · diamondAbstract read
In one paragraph

Article in Gland surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Anna Maria IerardiDepartment of Diagnostic and Interventiona Radiology, San Paolo Hospital, University of Milan, Milan, Italy.
Pierpaolo BiondettiDepartment of Diagnostic and Interventiona Radiology, San Paolo Hospital, University of Milan, Milan, Italy.
Andrea CoppolaDepartment of Radiology, Insubria University, Varese, Italy.
Enrico Maria FumarolaDepartment of Diagnostic and Interventiona Radiology, San Paolo Hospital, University of Milan, Milan, Italy.
Alberto Magenta BiasinaDepartment of Diagnostic and Interventiona Radiology, San Paolo Hospital, University of Milan, Milan, Italy.
Salvatore Alessio AngileriDepartment of Diagnostic and Interventiona Radiology, San Paolo Hospital, University of Milan, Milan, Italy.
Gianpaolo CarrafielloDepartment of Diagnostic and Interventiona Radiology, San Paolo Hospital, University of Milan, Milan, Italy.
Ospedale San Paolo · ITUniversity of Milan · ITUniversity of Insubria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn oncologic field, thermo-ablative procedures have spread more and more. Percutaneous microwave ablation (MWA) showed same benefits and some advantages over radiofrequency ablation (RFA). To date, a disadvantage of both was the not totally predictable size and shape of ablation volume. The aim of this study was to assess feasibility and safety of MWA in nonresectable pancreatic head cancer using a new technology of MW with high power (100 W) and frequency of 2,450 MH.

methodsFive patients with pancreatic head cancer treated with percutaneous MWA under ultrasound guidance were retrospectively reviewed. Mean lesion diameter was 27.8 mm (range, 25-32 mm). Follow-up was performed by CT after 1, 3, 6 and, when possible, 12 months. The shape of the ablation volume was evaluated with multiplanar reformatting (MPR) using roundness index (RI): a value near 1 represents a more spherical ablation zone shape, and a value distant from 1 implies an oval configuration. Ablation and procedure times were registered, together with hospital stay. The feasibility, safety and quality of life (QoL) were reported.

resultsThe procedure was feasible in all patients (100%). A spherical shape of ablation zone was achieved in all cases (mean RI =0.97). Mean ablation and procedure time were respectively of 2.48 and 28 minutes. Mean hospital stay was 4 days. No major complications were observed. Minor complications resolved during the hospital stay. An improvement in QoL was observed in all patients despite a tendency to return to preoperative levels in the months following the procedure.

conclusionsPercutaneous MWA is a feasible and safe approach for the palliative treatment of advanced stage tumors of the head of the pancreas, despite its complex anatomic relations. The spherical shape of the ablation volume could be related with an improving of the effectiveness and safety.

Indexed as

microwave ablation (MWA)palliative treatmentPancreatic tumorpercutaneousquality of life (QoL)

Identifiers

PMID29770302
PMCPMC5938265
OpenAlexW2772101056

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.