Evidence map›Paper›PMID 29770151›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

Research on Establishment of Abnormal Phlegmatic Syndrome with Premature Ovarian Failure Rat Model and Effects of Balgham Munziq Treatment.

Muladili Yuemaier, Mayire Tuerhong, Abulizi Keremu, Nafeisha Kadeer, Ayiguzhali Aimaiti, Xilinguli Wushouer, Adilijiang Yiming, Xiamixinuer Yilike

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Muladili YuemaierDepartment of Biology, School of Medicine, Xinjiang Medical University, Ürümqi, Xinjiang 830011, China.ORCID 0000-0002-8648-6325
Mayire TuerhongMorphology Center, School of Medicine, Xinjiang Medical University, Ürümqi, Xinjiang 830000, China.ORCID 0000-0003-1526-4706
Abulizi KeremuDepartment of Biology, School of Medicine, Xinjiang Medical University, Ürümqi, Xinjiang 830011, China.ORCID 0000-0003-1904-9982
Nafeisha KadeerDepartment of Biology, School of Medicine, Xinjiang Medical University, Ürümqi, Xinjiang 830011, China.ORCID 0000-0002-8207-4710
Ayiguzhali AimaitiDepartment of Biology, School of Medicine, Xinjiang Medical University, Ürümqi, Xinjiang 830011, China.ORCID 0000-0003-0715-0362
Xilinguli WushouerDepartment of Biology, School of Medicine, Xinjiang Medical University, Ürümqi, Xinjiang 830011, China.ORCID 0000-0003-2248-2779
Adilijiang YimingDepartment of Human Anatomy, School of Medicine, Xinjiang Medical University, Ürümqi, Xinjiang 830011, China.ORCID 0000-0002-9521-5615
Xiamixinuer YilikeDepartment of Biology, School of Medicine, Xinjiang Medical University, Ürümqi, Xinjiang 830011, China.ORCID 0000-0001-7500-3618
Xinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to establish and explore the biological basis of abnormal phlegmatic syndrome with premature ovarian failure (POF) model in rats based on the Uighur medicine (UM) in the first place and investigate the effects of unique herbal medicine, Balgham Munziq (BMq). Mature female Wistar rats were fed with spinach and coriander in cold and humid condition for approximately 20 weeks until abnormal phlegmatic syndrome (APS) model was established. When APS model was confirmed by Uighur medical experts, APS with POF disease rats were subdivided into APS with POF disease model group and APS with POF disease treated with BMq group; the rest of them were subdivided into APS model group and APS treated with BMq group. The results show that biological characteristics of animals in the course of modeling period were in accordance with clinical features of abnormal phlegmatic syndrome (APS) in Uighur medicine. Herbal medicine BMq not only reverted reproductive hormone levels disorders but also improved the function of hypothalamic-pituitary-ovarian axis and regulated secretion of monoamine neurotransmitters. APS is most likely to cause pathological changes of hypothalamic-pituitary-ovarian axis and lead to the occurrence of POF and BMq is effective in the treatment of APS with POF disease.

Identifiers

PMID29770151
PMCPMC5892281
OpenAlexW2792652975

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.