Evidence map›Paper›PMID 29770098›Full record

ArticleCanada communicable disease report = Releve des maladies transmissibles au Canada2018

Infectious and congenital syphilis in Canada, 2010-2015.

Y Choudhri, J Miller, J Sandhu, A Leon, J Aho

Open access · diamondAbstract read
In one paragraph

Article in Canada communicable disease report = Releve des maladies transmissibles au Canada, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.

  1. Pooled it
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  8. Penile ulcers in a 35-year-old man.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
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  13. Canadian Public Health Laboratory Network guidelines for the use of point-of-care tests forJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022
    Article
  14. Syphilis in Ottawa: An evolving epidemic.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
  15. A descriptive study of syphilis testing in Manitoba, Canada, 2015-2019.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
  16. Laboratory evaluation of two point-of-care test kits for the identification of infectious syphilis.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
  17. Delayed diagnosis of maternal and congenital syphilis: An unrecognized epidemic?Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Y ChoudhriCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
J MillerCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
J SandhuCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
A LeonCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
J AhoCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
Public Health Agency of Canada · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSyphilis is the third most commonly reported notifiable sexually transmitted infection (STI) in Canada, following chlamydia and gonorrhea, respectively. Rates of this STI have been rising rapidly in Canada since 2001.

objectiveTo summarize trends observed in syphilis rates for 2010 to 2015 in Canada.

methodsLaboratory-confirmed cases of infectious syphilis and early congenital syphilis were reported to the Public Health Agency of Canada by all of the Canadian provinces and territories. National infectious syphilis rates were computed, as were rates per sex, age group and province/territory. Rates of congenital syphilis were also calculated.

resultsFrom 2010 to 2015, the rate of infectious syphilis in Canada increased by 85.6%, from 5.0 to 9.3 cases per 100,000 population. In 2015, a total of 3,321 cases of infectious syphilis were reported, mainly in males (93.7%), among whom the rate was 17.5 cases per 100,000 males versus 1.2 per 100,000 females. The rate also rose faster among males in 2010-2015, a 90.2% increase versus 27.8% among females. Individuals aged 20-39 years had the highest rates. Across the provinces and territories, the highest rates of infectious syphilis were in Nunavut, British Columbia and Manitoba.

conclusionRates of syphilis continue to rise in Canada, especially among young men, and this is consistent with trends in the United States of America and European Union. Based on data from Canada and from these regions, the sexual behaviour of men who have sex with men (MSM) is thought to be a major risk factor for syphilis.

Identifiers

PMID29770098
PMCPMC5864261
OpenAlexW2793035228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.