Evidence map›Paper›PMID 29770052›Full record

ArticleCanada communicable disease report = Releve des maladies transmissibles au Canada2017

Surveillance of laboratory exposures to human pathogens and toxins: Canada 2016.

A Bienek, M Heisz, M Su

Abstract read
In one paragraph

Article in Canada communicable disease report = Releve des maladies transmissibles au Canada, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Surveillance of laboratory exposures to human pathogens and toxins, Canada, 2024.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  2. [Laboratory Biosafety Guideline (2025) Revision].Jugan geon-gang gwa jilbyeong · 2025
    Article
  3. Surveillance of laboratory exposures to human pathogens and toxins, Canada, 2023.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  4. Canadian laboratory incidents with human pathogens and toxins: An overview of reports, 2016-2022.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024
    Article
  5. Surveillance of laboratory exposures to human pathogens and toxins, Canada, 2021.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
  6. Multivariate analyses of risk factors associated with laboratory exposure incidents.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
  7. Laboratory-acquired infections in Canada from 2016 to 2021.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
  8. Review
  9. Surveillance of laboratory exposures to human pathogens and toxins, Canada 2020.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021
    Article
  10. Assessment of biorisk management systems in high containment laboratories, 18 countries in Europe, 2016 and 2017.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020
    Article
  11. Surveillance of laboratory exposures to human pathogens and toxins: Canada 2018.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2019
    Article
  12. Surveillance of laboratory exposures to human pathogens and toxins: Canada 2017.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A BienekCentre for Biosecurity, Public Health Agency of Canada, Ottawa, ON.
M HeiszCentre for Biosecurity, Public Health Agency of Canada, Ottawa, ON.
M SuCentre for Biosecurity, Public Health Agency of Canada, Ottawa, ON.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCanada recently enacted legislation to authorize the collection of data on laboratory incidents involving a biological agent. This is done by the Public Health Agency of Canada (PHAC) as part of a comprehensive national program that protects Canadians from the health and safety risks posed by human and terrestrial animal pathogens and toxins.

objectiveTo describe the first year of data on laboratory exposure incidents and/or laboratory-acquired infections in Canada since the

methodsIncidents that occurred between January 1 and December 31, 2016 were self-reported by federally-regulated parties across Canada using a standardized form from the Laboratory Incident Notification Canada (LINC) surveillance system. Exposure incidents were described by sector, frequency of occurrence, timeliness of reporting, number of affected persons, human pathogens and toxins involved, causes and corrective actions taken. Microsoft Excel 2010 was used for basic descriptive analyses.

resultsIn 2016, 46 exposure incidents were reported by holders of 835 active licences in Canada representing 1,352 physical areas approved for work involving a biological agent, for an overall incidence of 3.4%. The number of incidents was highest in the academic (n=16; 34.8%) and hospital (n=12; 26.1%) sectors, while the number of reported incidents was relatively low in the private industry sector. An average of four to five incidents occurred each month; the month of September presented as an outlier with 10 incidents.

conclusionsThe Laboratory Incident Notification Canada is one of the first surveillance systems in the world to gather comprehensive data on laboratory incidents involving human pathogens and toxins. Exposure incidents reported in the first year were relatively rare, occurring in less than 4% of containment zones within laboratory settings.

Identifiers

PMID29770052
PMCPMC5764741

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.