ArticleCanada communicable disease report = Releve des maladies transmissibles au Canada2014
Lyme disease: clinical diagnosis and treatment.
Article in Canada communicable disease report = Releve des maladies transmissibles au Canada, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 64 citations in OpenAlex.
- Lessons Unlearned: The Barriers to Lyme Borreliosis Vaccination and the Risk of Repeating History.Vaccines · 2026Article
- Persistent bradycardia requiring temporary pacing in a young adult with lyme carditis: a case report.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Article
- Post-Exposure Prophylaxis Prescribing Practices in a Lyme Disease-Endemic Area.Infectious disease reports · 2026Article
- Borrelia burgdorferi-Induced Neuroinflammation in Lyme Disease: A Potential Driver of Alzheimer's Disease Pathology?Molecular neurobiology · 2026Review
- Tick-borne rash at the surgical site prior to lung cancer resection: a diagnostic and surgical dilemma case report.AME case reports · 2026Article
- Lyme Disease Presenting as Rupture Baker's Cyst: Case Report and Literature Review.Clinical medicine insights. Case reports · 2026Article
- Article
- Atypical presentation of Lyme disease in a returning traveler: a case report.Tropical diseases, travel medicine and vaccines · 2025Article
- Silent Spread ofHealthcare (Basel, Switzerland) · 2025Article
- Anaplasmosis: Emerging threat in Canada.Canadian family physician Medecin de famille canadien · 2025Review
- Article
- Synthesis of aMolecules (Basel, Switzerland) · 2024Article
- Estimating the Incidence and Economic Cost of Lyme Disease Cases in Canada in the 21st Century with Projected Climate Change.Environmental health perspectives · 2024Article
- Lyme radiculopathy in a septuagenarian.BMJ case reports · 2023Article
- Article
- Modified Two-Tiered Testing Enzyme Immunoassay Algorithm for Serologic Diagnosis of Lyme Disease.Open forum infectious diseases · 2022Article
- Surveillance for Lyme disease in Canada, 2009-2019.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022Article
- Introduction of IgM testing for the diagnosis of acute Lyme borreliosis: a study of the benefits, limitations and costs.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022Article
- Occupational Lyme Disease: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2022Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLyme disease is an emerging zoonotic infection in Canada. As the
objectiveTo review the clinical diagnosis and treatment of Lyme disease for front-line clinicians.
methodsA literature search using PubMed and restricted to articles published in English between 1977 and 2014.
resultsIndividuals in Lyme-endemic areas are at greatest risk, but not all tick bites transmit Lyme disease. The diagnosis is predominantly clinical. Patients with Lyme disease may present with early disease that is characterized by a "bull's eye rash", fever and myalgias or with early disseminated disease that can manifest with arthralgias, cardiac conduction abnormalities or neurologic symptoms. Late Lyme disease in North America typically manifests with oligoarticular arthritis but can present with a subacute encephalopathy. Antibiotic treatment is effective against Lyme disease and works best when given early in the infection. Prophylaxis with doxycyline may be indicated in certain circumstances. While a minority of patients may have persistent symptoms, evidence does not demonstrate that prolonged courses of antibiotics improve outcome.
conclusionClinicians need to be aware of the signs and symptoms of Lyme disease. Knowing the regions where
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.