Structural and Biomechanical Adaptations to Free-Fall Landing in Hindlimb Cortical Bone of Growing Female Rats.

Hsin-Shih Lin, Ho-Seng Wang, Hung-Ta Chiu, Kuang-You B Cheng, Ar-Tyan Hsu, Tsang-Hai Huang

Open access · greenAbstract read

In one paragraph

Article in Journal of sports science & medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 47% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

Exercise Alleviates Osteoporosis in Rats with Mild Chronic Kidney Disease by Decreasing Sclerostin Production.International journal of molecular sciences · 2019
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hsin-Shih LinInstitute of Physical Education, Health and Leisure Studies, National Cheng Kung University, Tainan, Taiwan.

Ho-Seng WangDepartment of Physical Education, National Taiwan Normal University, Taipei, Taiwan.

Hung-Ta ChiuInstitute of Physical Education, Health and Leisure Studies, National Cheng Kung University, Tainan, Taiwan.

Kuang-You B ChengInstitute of Physical Education, Health and Leisure Studies, National Cheng Kung University, Tainan, Taiwan.

Ar-Tyan HsuDepartment of Physical Therapy, National Cheng Kung University, Tainan, Taiwan.

Tsang-Hai HuangInstitute of Physical Education, Health and Leisure Studies, National Cheng Kung University, Tainan, Taiwan.

National Cheng Kung University · TWNational Taiwan Normal University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the study was to investigate the adaptation process of hindlimb cortical bone subjected to free-fall landing training. Female Wistar rats (7 weeks old) were randomly assigned to four landing (L) groups and four age-matched control (C) groups (n = 12 per group): L1, L2, L4 L8, C1, C2, C4 and C8. Animals in the L1, L2, L4 and L8 groups were respectively subjected to 1, 2, 4 and 8 weeks of free-fall-landing training (40 cm height, 30 times/day and 5 days/week) while the C1, C2, C4 and C8 groups served as age-matched control groups. The tibiae of the L8 group were higher in cortical bone mineral content (BMC) than those in the C8 group (p < 0.05). Except for the higher bone mineralization over bone surface ratio (MS/BS, %) shown in the tibiae of the L1 group (p < 0.05), dynamic histomorphometry in the tibial and femoral cortical bone showed no difference between landing groups and their age-matched control groups. In the femora, the L1 group was lower than the C1 group in cortical bone area (Ct.Ar) and cortical thickness (Ct.Th) (p < 0.05); however, the L4 group was higher than the C4 group in Ct.Ar and Ct.Th (p <0 .05). In the tibiae, the moment of inertia about the antero-posterior axis (

Indexed as

Adaptation, PhysiologicalBone DensityBone DevelopmentAnimalsBiomechanical PhenomenaCortical BoneFemaleFemurHindlimbPhysical Conditioning, AnimalRandom AllocationRats, WistarTibiaanimal modelbone strengthexerciseMechanical loading

Identifiers

PMID29769819

PMCPMC5950735

OpenAlexW2802823526

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.