Evidence map›Paper›PMID 29769764›Full record

ArticleJournal of Indian Society of Periodontology

Association of pentraxin and high-sensitive C-reactive protein as inflammatory biomarkers in patients with chronic periodontitis and peripheral arterial disease.

Ramanarayana Boyapati, Srikanth Chinthalapani, Arpita Ramisetti, Shyam Sunder Salavadhi, Radhika Ramachandran

Open access · diamondAbstract read
In one paragraph

Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ramanarayana BoyapatiDepartment of Periodontics, Mamata Dental College, Khammam, Telangana, India.
Srikanth ChinthalapaniDepartment of Periodontics, Mamata Dental College, Khammam, Telangana, India.
Arpita RamisettiDepartment of Periodontics, Mamata Dental College, Khammam, Telangana, India.
Shyam Sunder SalavadhiDepartment of Periodontics, Mamata Dental College, Khammam, Telangana, India.
Radhika RamachandranDepartment of Periodontics, Mamata Dental College, Khammam, Telangana, India.
Mamata Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextInflammation is a common feature of both peripheral artery disease (PAD) and periodontal disease.

aimThe aim of this study is to evaluate the relationship between PAD and periodontal disease by examining the levels of inflammatory cytokines, pentraxin-3 (PTX-3), and high-sensitive C-reactive protein from serum. MATERIALS AND

methodsA total of 50 patients were included in this cross-sectional study. Patients were divided into two groups: those with PAD (test group) and those with the non-PAD group (control group) based on ankle-brachial index values. Periodontal examinations and biochemical analysis for PTX-3 and high-sensitive C-reactive protein were performed to compare the two groups. STATISTICAL ANALYSIS USED: All the obtained data were sent for statistical analyses using SPSS version 18.

resultsIn the clinical parameters, there is statistically significant difference present between plaque index, clinical attachment loss, and periodontal inflammatory surface area with higher mean values in patients with PAD having periodontitis. There is statistical significant (

conclusionPTX-3 and acute-phase cytokine such as hs-CRP can be regarded as one of the best indicators to show the association between the PAD and periodontitis followed by hs-CRP, TC, very LDL (VLDL), and LDL. However, high-density lipoprotein (HDL) is a poor indicator for its association with chronic periodontitis and PAD.

Indexed as

Biomarkerchronic periodontitisC-reactive proteinpentraxin-3peripheral artery disease

Identifiers

PMID29769764
PMCPMC5939017
OpenAlexW2800108544

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.