Evidence map›Paper›PMID 29769703›Full record

ArticleInternational journal of obesity (2005)2019

Preoperative thyroid function and weight loss after bariatric surgery.

João Sérgio Neves, Pedro Souteiro, Sofia Castro Oliveira, Jorge Pedro, Daniela Magalhães, Vanessa Guerreiro, Maria Manuel Costa, Rita Bettencourt-Silva, Ana Cristina Santos, Joana Queirós and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of obesity (2005), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. The Impact of Laparoscopic Sleeve Gastrectomy on Thyroid Functions in Egyptian Patients with Obesity.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
  3. Targeting skeletal muscle mitochondrial health in obesity.Clinical science (London, England : 1979) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

João Sérgio NevesDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal. joaosergioneves@gmail.com.ORCID http://orcid.org/0000-0002-8173-8255
Pedro SouteiroDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Sofia Castro OliveiraDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Jorge PedroDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Daniela MagalhãesDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Vanessa GuerreiroDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Maria Manuel CostaDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Rita Bettencourt-SilvaDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Ana Cristina SantosDepartamento de Ciências da Saúde Pública e Forenses e Educação Médica, Faculdade de Medicina, Universidade do Porto, Porto, Portugal.
Joana QueirósDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Ana VarelaDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Paula FreitasDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Davide CarvalhoDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
AMTCO Group
Universidade do Porto · PTHospital de São João · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid function has an important role on body weight regulation. However, the impact of thyroid function on weight loss after bariatric surgery is still largely unknown. We evaluated the association between preoperative thyroid function and the excess weight loss 1 year after surgery, in 641 patients with morbid obesity who underwent bariatric surgery. Patients with a history of thyroid disease, treatment with thyroid hormone or antithyroid drugs and those with preoperative evaluation consistent with overt hypothyroidism or hyperthyroidism were excluded. The preoperative levels of TSH and FT4 were not associated with weight loss after bariatric surgery. The variation of FT3 within the reference range was also not associated with weight loss. In contrast, the subgroup with FT3 above the reference range (12.3% of patients) had a significantly higher excess weight loss than patients with normal FT3. This difference remained significant after adjustment for age, sex, BMI, type of surgery, TSH and FT4. In conclusion, we observed an association between high FT3 and a greater weight loss after bariatric surgery, highlighting a group of patients with an increased benefit from this intervention. Our results also suggest a novel hypothesis: the pharmacological modulation of thyroid function may be a potential therapeutic target in patients undergoing bariatric surgery.

Indexed as

AdultBariatric SurgeryFemaleHumansMaleMiddle AgedObesity, MorbidPreoperative PeriodRetrospective StudiesThyroid HormonesWeight LossThyroid Hormones

Identifiers

PMID29769703
OpenAlexW2804901538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.