ArticleBioscience reports2019
Knockdown of Rab7a suppresses the proliferation, migration, and xenograft tumor growth of breast cancer cells.
Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Exosomal microRNA-448 suppresses the malignant behaviors of liver cancer cells by targeting RAB7A and inhibiting glycolysis.Oncology letters · 2026Article
- CTH Promotes Liver Cancer Progression and Exploratory Evaluation Supports Enhanced Antitumor Activity of PPG Plus GPC3 CAR-T Cells.Journal of immunology research · 2026Article
- Comprehensive Analysis of scRNA-Seq and Bulk RNA-Seq Identified TIMP1 as a Prognostic Marker in Colorectal Cancer.Immune network · 2025Article
- Rab7a is an enhancer of TPC2 activity regulating melanoma progression through modulation of the GSK3β/β-Catenin/MITF-axis.Nature communications · 2024Article
- The role of Golgi complex proteins in cell division and consequences of their dysregulation.Frontiers in cell and developmental biology · 2024Review
- miR-3200 accelerates the growth of liver cancer cells by enhancing Rab7A.Non-coding RNA research · 2023Article
- [High expression of RAB7A is associated with poor prognosis of gastric cancer by promoting tumor invasion].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023Article
- Extracellular Hydraulic Resistance Enhances Cell Migration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Repurposing Oxiconazole against Colorectal Cancer via PRDX2-mediated Autophagy Arrest.International journal of biological sciences · 2022Article
- Bayesian Gene Selection Based on Pathway Information and Network-Constrained Regularization.Computational and mathematical methods in medicine · 2021Article
- Thiazole-Based Thiosemicarbazones: Synthesis, Cytotoxicity Evaluation and Molecular Docking Study.Drug design, development and therapy · 2021Article
- Evidence for Enhanced Exosome Production in Aromatase Inhibitor-Resistant Breast Cancer Cells.International journal of molecular sciences · 2020Article
- Rab7 Is Associated with Poor Prognosis of Gastric Cancer and Promotes Proliferation, Invasion, and Migration of Gastric Cancer Cells.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Defining an embryonal rhabdomyosarcoma endotype.Cold Spring Harbor molecular case studies · 2020Article
- Article
- Tumor-derived exosomes (TDEs): How to avoid the sting in the tail.Medicinal research reviews · 2020Review
- Article
Corrections and comments
- Expression of concern
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer is a common invasive cancer in women. Ras-related protein Rab-7a (Rab7a) is involved in late endocytic trafficking, while its role in breast cancer is largely unclear. In the present study, we investigated the role of Rab7a in breast cancer. Comparing with adjacent breast tissues, Rab7a expression was increased in breast cancer tissues. Using lentivirus-mediated knockdown strategy, we found that Rab7a silencing inhibited the proliferation and colony formation of MDA-MB-231 cells. Apoptosis and G
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