Evidence map›Paper›PMID 29769402›Full record

ArticleThe EMBO journal2018

GTSF-1 is required for formation of a functional RNA-dependent RNA Polymerase complex in

Miguel Vasconcelos Almeida, Sabrina Dietz, Stefan Redl, Emil Karaulanov, Andrea Hildebrandt, Christian Renz, Helle D Ulrich, Julian König, Falk Butter, René F Ketting

Open access · bronzeAbstract read
In one paragraph

Article in The EMBO journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  3. Review
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  6. Abundant piRNA production mediated by theProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Developmental roles and molecular mechanisms of Asterix/GTSF1.Wiley interdisciplinary reviews. RNA · 2022
    Review
  12. Biogenesis ofScience advances · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Miguel Vasconcelos AlmeidaBiology of Non-coding RNA Group, Institute of Molecular Biology, Mainz, Germany.ORCID 0000-0002-4816-3111
Sabrina DietzQuantitative Proteomics Group, Institute of Molecular Biology, Mainz, Germany.
Stefan RedlBiology of Non-coding RNA Group, Institute of Molecular Biology, Mainz, Germany.
Emil KaraulanovBioinformatics Core Facility, Institute of Molecular Biology, Mainz, Germany.
Andrea HildebrandtGenomic Views of Splicing Regulation Group, Institute of Molecular Biology, Mainz, Germany.
Christian RenzMaintenance of Genome Stability Group, Institute of Molecular Biology, Mainz, Germany.
Helle D UlrichMaintenance of Genome Stability Group, Institute of Molecular Biology, Mainz, Germany.
Julian KönigGenomic Views of Splicing Regulation Group, Institute of Molecular Biology, Mainz, Germany.
Falk ButterQuantitative Proteomics Group, Institute of Molecular Biology, Mainz, Germany.ORCID 0000-0002-7197-7279
René F KettingBiology of Non-coding RNA Group, Institute of Molecular Biology, Mainz, Germany r.ketting@imb-mainz.de.ORCID 0000-0001-6161-5621
Institute of Molecular Biology · DE

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Argonaute proteins and their associated small RNAs (sRNAs) are evolutionarily conserved regulators of gene expression. Gametocyte-specific factor 1 (Gtsf1) proteins, characterized by two tandem CHHC zinc fingers and an unstructured C-terminal tail, are conserved in animals and have been shown to interact with Piwi clade Argonautes, thereby assisting their activity. We identified the

Indexed as

Gene SilencingAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsMutationRNA-Dependent RNA PolymeraseRNA, HelminthRNA, UntranslatedCaenorhabditis elegans ProteinsRNA-Dependent RNA PolymeraseRNA, HelminthRNA, Untranslated26G‐RNAC. elegansGTSFpiRNARdRP

Identifiers

PMID29769402
PMCPMC6003641
OpenAlexW2803862617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.