Evidence map›Paper›PMID 29769309›Full record

ArticleThe Journal of biological chemistry2018

Etoposide-induced protein 2.4 functions as a regulator of the calcium ATPase and protects pancreatic β-cell survival.

Lin Yuan, Huiyu Wang, Qi Liu, Zhe Wang, Mingshu Zhang, Yan Zhao, Kuo Liang, Liangyi Chen, Tao Xu, Pingyong Xu

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Restoration of Sarcoplasmic Reticulum CaInternational journal of molecular sciences · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Lin YuanFrom the Key Laboratory of RNA Biology and.
Huiyu WangFrom the Key Laboratory of RNA Biology and.
Qi LiuFrom the Key Laboratory of RNA Biology and.
Zhe WangFrom the Key Laboratory of RNA Biology and.
Mingshu ZhangFrom the Key Laboratory of RNA Biology and.
Yan Zhaothe National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101.
Kuo Liangthe Department of General Surgery, XuanWu Hospital, Capital Medical University, Beijing 100053, and.
Liangyi Chenthe State Key Laboratory of Biomembrane and Membrane Biotechnology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing 100871, China.
Tao Xuthe College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100101, xutao@ibp.ac.cn.
Pingyong XuFrom the Key Laboratory of RNA Biology and pyxu@ibp.ac.cn.
Chinese Academy of Sciences · CNUniversity of Chinese Academy of Sciences · CNCapital Medical University · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium homeostasis is essential for maintaining the viability and function of pancreatic β cells and plays a key role in preventing the development of diabetes. Decreased levels of ATPase sarcoplasmic/endoplasmic reticulum Ca

Indexed as

AMP-Activated Protein KinasesAnimalsApoptosis Regulatory ProteinsCalciumCalcium-Calmodulin-Dependent Protein Kinase KinaseCell LineCell SurvivalDiabetes MellitusEnergy MetabolismGene Knockout TechniquesHomeostasisHumansInsulin-Secreting CellsMiceNuclear ProteinsPhenotypeAMP-Activated Protein KinasesApoptosis Regulatory ProteinsATP2A2 protein, humanAtp2a2 protein, mouseCalciumCalcium-Calmodulin-Dependent Protein Kinase KinaseCamkk2 protein, mouseEI24 protein, humanEI24 protein, mouseNuclear ProteinsSarcoplasmic Reticulum Calcium-Transporting ATPasesapoptosisATPase sarcoplasmic/endoplasmic reticulum Ca2+-transporting 2calcium ATPasecell metabolismdiabetesetoposide-induced protein 2.4glucose tolerancepancreatic islet

Identifiers

PMID29769309
PMCPMC6028951
OpenAlexW2804838225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.