Evidence map›Paper›PMID 29769021›Full record

ReviewEnvironmental health and preventive medicine2018

The toxicological mechanisms and detoxification of depleted uranium exposure.

Yong-Chao Yue, Ming-Hua Li, Hai-Bo Wang, Bang-Le Zhang, Wei He

Open access · goldAbstract readReview
In one paragraph

Review in Environmental health and preventive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. A State-of-the-Science Review on Metal Biomarkers.Current environmental health reports · 2023
    Review
  9. Characterization of Uranyl (UOACS chemical neuroscience · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Uranium: The Nuclear Fuel Cycle and Beyond.International journal of molecular sciences · 2022
    Review
  17. Review
  18. Article
  19. Acute toxic kidney injury.Renal failure · 2019
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yong-Chao YueDepartment of Chemistry, School of Pharmacy, Fourth Military Medical University, No. 169 Changle West Road, Xi'an, 710032, Shaanxi, People's Republic of China.ORCID http://orcid.org/0000-0002-7585-3900
Ming-Hua LiDepartment of Chemistry, School of Pharmacy, Fourth Military Medical University, No. 169 Changle West Road, Xi'an, 710032, Shaanxi, People's Republic of China.
Hai-Bo WangDepartment of Chemistry, School of Pharmacy, Fourth Military Medical University, No. 169 Changle West Road, Xi'an, 710032, Shaanxi, People's Republic of China.
Bang-Le ZhangDepartment of Pharmaceutics, School of Pharmacy, Fourth Military Medical University, No. 169 Changle West Road, Xi'an, 710032, Shaanxi, People's Republic of China. blezhang@fmmu.edu.cn.
Wei HeDepartment of Chemistry, School of Pharmacy, Fourth Military Medical University, No. 169 Changle West Road, Xi'an, 710032, Shaanxi, People's Republic of China. weihechem@fmmu.edu.cn.
Air Force Medical University · CN

Funding

National Science and Technology Major Project of China 2014ZX09J14104-06C
6 · The paper itself

Abstract

Depleted uranium (DU) has been widely applied in industrial and military activities, and is often obtained from producing fuel for nuclear reactors. DU may be released into the environment, polluting air, soil, and water, and is considered to exert both radiological and chemical toxicity. In humans and animals, DU can induce multiple health effects, such as renal tubular necrosis and bone malignancies. This review summarizes the known information on DU's routes of entry, mechanisms of toxicity, and health effects. In addition, we survey the chelating agents used in ameliorating DU toxicity.

Indexed as

AnimalsChelating AgentsHumansInactivation, MetabolicRadiation-Protective AgentsUraniumChelating AgentsRadiation-Protective AgentsUraniumChelating agentsDecorporationDepleted uraniumToxicity

Identifiers

PMID29769021
PMCPMC5956823
OpenAlexW2803617198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.