Evidence map›Paper›PMID 29768673›Full record

ArticleBritish journal of clinical pharmacology2018

The use of complementary and alternative medicines during breastfeeding: results from the Herbal supplements in Breastfeeding InvesTigation (HaBIT) study.

Alessandra Bettiol, Niccolò Lombardi, Ettore Marconi, Giada Crescioli, Roberto Bonaiuti, Valentina Maggini, Eugenia Gallo, Alessandro Mugelli, Fabio Firenzuoli, Claudia Ravaldi and 1 more

Abstract read
In one paragraph

Article in British journal of clinical pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Self-Learning about Herbal and Dietary Supplements: Perspectives Using the Theoretical Domains Framework.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alessandra BettiolDepartment of Neurosciences, Psychology, Drug Research and Child Health Section of Pharmacology and Toxicology, University of Florence; Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Niccolò LombardiDepartment of Neurosciences, Psychology, Drug Research and Child Health Section of Pharmacology and Toxicology, University of Florence; Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Ettore MarconiDepartment of Neurosciences, Psychology, Drug Research and Child Health Section of Pharmacology and Toxicology, University of Florence; Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Giada CrescioliDepartment of Neurosciences, Psychology, Drug Research and Child Health Section of Pharmacology and Toxicology, University of Florence; Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Roberto BonaiutiDepartment of Neurosciences, Psychology, Drug Research and Child Health Section of Pharmacology and Toxicology, University of Florence; Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Valentina MagginiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Eugenia GalloDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Alessandro MugelliDepartment of Neurosciences, Psychology, Drug Research and Child Health Section of Pharmacology and Toxicology, University of Florence; Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Fabio FirenzuoliCenter for Integrative Medicine, Careggi University Hospital, University of Florence, Florence, Italy.
Claudia RavaldiCiaoLapo Onlus, Charity for Healthy Pregnancy, Stillbirth and Perinatal Grief Support, Prato, Italy.
Alfredo VannacciDepartment of Neurosciences, Psychology, Drug Research and Child Health Section of Pharmacology and Toxicology, University of Florence; Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.ORCID 0000-0001-5259-2026

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe use of complementary and alternative medicines (CAMs) during breastfeeding is increasing, mainly because of their presumed greater safety compared with conventional medications. However, CAMs can cause serious adverse effects, and there is limited high-quality evidence supporting their use during lactation. In Italy, specific investigations on the attitude of lactating women towards CAMs are lacking. The Herbal supplements in Breastfeeding InvesTigation (HaBIT) study aimed to explore attitudes to and knowledge on CAMs among lactating women.

methodsA web-based survey was conducted over a 6-year period among lactating women resident in Tuscany, Italy. Data on lactating behaviour, CAMs use during pregnancy or breastfeeding, and women's knowledge about the efficacy and safety of CAMs were collected.

resultsA total of 388 lactating women answered the questionnaire. The majority of them were primiparae, with a high educational level. Of these, 204 women declared themselves to have used CAMs during breastfeeding. Moreover, 61% and 48% of subjects reported also using CAMs before and during pregnancy, respectively. A significant proportion of subjects were unable to identify correctly the types of CAMs they were using. Seventy-three per cent of women were convinced that CAMs were equally safe or safer than conventional medications; nevertheless, 65% of women admitted to have no scientific information about the potential risks of CAMs, and 14 CAMs users reported that they had experienced side effects.

conclusionsThese results demonstrate the need for healthcare providers to increase the awareness of breastfeeding women about CAMs. Further research is needed to support the evidence base for nonpharmaceutical approaches for symptom control during breastfeeding.

Indexed as

Breast FeedingHealth Knowledge, Attitudes, PracticeAdultComplementary TherapiesDietary SupplementsFemaleHumansInfantItalyLactationPatient Education as TopicPregnancySurveys and Questionnairesadverse drug reactionsbreastfeedingcomplementary medicineherbal medicinepregnancy

Identifiers

PMID29768673
PMCPMC6089807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.