ArticlePloS one2018
Urinary shedding of pathogenic Leptospira in stray dogs and cats, Algiers: A prospective study.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 44 citations in OpenAlex.
- Pathogenic Leptospira species identified in dogs and cats during neutering in Thailand.PLoS neglected tropical diseases · 2026Article
- Leptospira and Leptospirosis: A Review of Species Classifications, Genomes, Morphological Structures, Antimicrobial Resistances, Transmissions, and Clinical Manifestations.Current microbiology · 2026Review
- Molecular identification and phylogenetic characterization ofJournal of advanced veterinary and animal research · 2026Article
- Seroprevalence and carrier status ofIranian journal of veterinary research · 2025Article
- Grenadian cats as potential reservoir for Leptospira.PLoS neglected tropical diseases · 2024Article
- Surveillance of Emerging Rodent-Borne Pathogens in Wastewater in Taiwan: A One Health Approach.Tropical medicine and infectious disease · 2024Article
- Article
- Domestic dogs in indigenous Amazonian communities: Key players in Leptospira cycling and transmission?PLoS neglected tropical diseases · 2024Article
- Feline leptospirosis prevalence worldwide: A systematic review and meta-analysis of diagnostic approaches.Veterinary world · 2024Article
- First Molecular Detection of PathogensTropical medicine and infectious disease · 2022Article
- Article
- Serological and molecular detection of pathogenicEpidemiology and infection · 2021Article
- Molecular and serological epidemiology of Leptospira infection in cats in Okinawa Island, Japan.Scientific reports · 2021Article
- Persistent High Leptospiral Shedding by Asymptomatic Dogs in Endemic Areas Triggers a Serious Public Health Concern.Animals : an open access journal from MDPI · 2021Article
- Detection ofVeterinary world · 2020Article
- An Observational Study of Human Leptospirosis in Seychelles.The American journal of tropical medicine and hygiene · 2020Observational
- Leptospira infection and shedding in dogs in Thailand.BMC veterinary research · 2020Article
- Article
- Leptospirosis in cats: Current literature review to guide diagnosis and management.Journal of feline medicine and surgery · 2020Review
- Leptospira interrogans and Leptospira kirschneri are the dominant Leptospira species causing human leptospirosis in Central Malaysia.PLoS neglected tropical diseases · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLeptospirosis is an important worldwide zoonosis. This disease is caused by pathogenic species of the genus Leptospira which are maintained in the environment via chronic renal infection of carrier animals which can be asymptomatic excretors of the organisms in their urines and become a source of infection for humans and other hosts. The prevalence of animal leptospirosis in Algiers, Algeria, is unknown. METHODOLOGY/PRINCIPAL
findingsReal-time PCR and standard PCR and sequencing were used to detect pathogenic Leptospira organisms in the urines of stray dogs and cats in Algiers. In the presence of appropriate controls, none of the 107 cat urine samples were positive while 5/104 (4.8%) canine urine samples (asymptomatic mixed-breed dogs, three females and two males) were positive in two real-time PCR assays targeting the rrs and hsp genes. The positivity of these samples was confirmed by partial PCR-sequencing of the rpoB gene which yielded 100% sequence similarity with Leptospira interrogans reference sequence. In this study, L. interrogans prevalence was significantly higher in dogs aged < one year (16.46% - 29.41%) than in adults (0%) (P value = 0.0001) and then in the overall dog population (2.68% - 4.8%) (P = 0.0007). CONCLUSIONS/SIGNIFICANCE: These results suggest that dogs are maintenance hosts for zoonotic leptospirosis in Algiers, Algeria. To face this situation, effective canine vaccination strategies and raising public health awareness are mandatory. Further investigations incorporating a larger sample in more localities will be undertaken to document the epidemiology of urban animal leptospirosis in Algeria at large.
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Registered trials
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